DRKS00034088招募中不适用

Intestinal fatty acid-binding protein (I-FAB) for the early diagnosis of acute mesenteric ischemia - I-FAB

niversitätsklinikum Dresden, Klinik und Poliklinik für Viszeral-, Thorax- und Gefäßchirurgie0 个研究点目标入组 20 人开始时间: 2024年4月17日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patients with subsequent elective surgery can be included in the study:
•- open thoracoabdominal aortic replacement
•- aortic replacement with suprarenal clamping
•- complex endovascular aortic repair with stenting of visceral vessels
•- complicated type B aortic dissections.
•Over a period of 24 months, all patients with unspecific or specific symptoms of acute mesenteric ischemia (AMI) will be examined for three inclusion criteria for the study in addition to the above-mentioned patients:
•(1) Clinical: Urgent clinical suspicion of AMI, e.g. acute abdomen with sudden onset of pain, history of angina abdominalis, severe intestinal patency disorder with increasing or persistent need for vasopressors
•(2) Serological: lactatemia with an initial increase above 2.5 mmol/l or persistent values above 5.0 mmol/l over 12 hours postoperatively
•(3) Instrumental: Endoscopic evidence (ischemic mucosa, transmural necrosis) or computed tomography evidence (pneumatosis intestinalis, occlusion of visceral vessels). In addition, intraoperative measurement of intestinal blood flow using indocyanine green (ICG) in suspected cases of reduced blood flow.

•- pregnancy
•- lack of written consent from the patient or their legal representative within 96 hours of study inclusion (preoperatively)
•- patients who are unable to participate in the study due to lack of compliance or language skills

发起方

niversitätsklinikum Dresden, Klinik und Poliklinik für Viszeral-, Thorax- und Gefäßchirurgie