To compare the effect of additive(dexmedetomidine) to pain reducing drug(0.25% bupivacaine) in prolonging postoperative analgesia after injecting into diseased breast in breast cancer patients undergoing breast surgeries
Phase 2
- Conditions
- Health Condition 1: null- Age group between 18 to 70 years female patients belonging to ASAPS 1 or 2 undergoing modified radical mastectomy for breast cancer
- Registration Number
- CTRI/2018/03/012785
- Lead Sponsor
- PG Thesis fund KMC Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All female patients undergoing Modified Radical Mastectomy under general anaesthesia belonging to ASAPS 1 or 2
2.Patients aged between 18 years to 70 years
3.Patients who are alert,conscious and cooperative
Exclusion Criteria
Patientâ??s refusal
History of allergy to the medications used in
the study
Contraindications to regional
anesthesia(including coagulopathy and local
infection)
Prior breast surgery except for diagnostic
biopsies
History of treatment for a chronic pain
condition and/or psychiatric disorder
Pregnant women
Patients in whom tumour is located at the site of needle insertion for drug injection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Requirement of rescue analgesicsTimepoint: asess patients pain intensity and analgesia satisfaction in the post-operative period at 0min,30mins,1hr,2hrs,4hrs,6hrs,8hrs,12hrs,16hrs,20hrs and 24hrs
- Secondary Outcome Measures
Name Time Method Patient comfortTimepoint: Every 4th hrly during the first 12hrs of post-operative period;Post operative nausea and vomitingTimepoint: within 24hrs postoperative period;Sedation score(based on Ramsay Sedation Score)Timepoint: Asessed at 0hrs,2hrs,4hrs,8hrs,12hrs,16hrs,20hrs and 24hrs of post-operative period