The effects of curcumin-piperne supplementation on CABG patient

Phase 3

Conditions: Cardiovascular disease.
Atherosclerotic heart disease of native coronary artery
I25.1

Registration Number: IRCT20201129049534N4

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 80

Inclusion Criteria

Age 30-80 years
Gastrointestinal normal function and with intestinal or oral nutrition criteria
Ejection fraction (EF) above 15%
Arrest Time (cardiac resuscitation) 30 to 90 minutes
Willingness to participate in the study and complete the consent form before surgery

Exclusion Criteria

Allergy to herbal products such as turmeric and pepper
Taking herbal supplements (as a supplement) during 3 months before the operation
Need for emergency surgery
Requires balloon pump
Adding another operation in addition to CABG, like simultaneous valve operation
Patients who do not have an indication for intestinal or oral nutrition on the first day of the intervention and are expected to be unable to receive intestinal or oral nutrition in the future
Patients with a history of underlying disease such as congenital and immune disorders and pancreatitis
Pregnancy and lactation

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
C reactive Protein (CRP). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Blood urea nitrogen (BUN). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Creatinine (Cr). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Lactate Dehydrogenase (LDH). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;CK-MB. Timepoint: At baseline and end of the study. Method of measurement: Commercial diagnostic kit.;Troponin. Timepoint: At baseline and end of the study. Method of measurement: Commercial diagnostic kit.

Secondary Outcome Measures

Name	Time	Method
28-days mortality rate. Timepoint: End of the study. Method of measurement: Mathematically dividing the number of dead people by the total number of people using hospital records or telephone follow-up.;Atrial fibrillation. Timepoint: End of the study. Method of measurement: Electrocardiogram (ECG or EKG).