Vitamin D Supplementation in Wheelchair Indoor Athletes

Not Applicable

Completed

• Conditions: Physical Education and Training/Methods; Drug Effects; Dietary Supplements; Vitamin D Deficiency; Spinal Cord Injury
• Interventions: Dietary Supplement: Vitamin D; Dietary Supplement: Placebo

• Registration Number: NCT02621320
• Lead Sponsor: Swiss Paraplegic Research, Nottwil

Brief Summary

There is a high prevalence of vitamin D deficiency in Switzerland. In indoor-athletes as well as wheelchair users, vitamin D deficiency occurs even more often. It is well established that vitamin D deficiency has a negative effect on health. However, vitamin D supplementation in individuals with a vitamin D deficiency has a positive effect on muscle performance. In recently published studies with able-bodied subjects, it has been shown that a normal vitamin D level (\>75nmol/L) can only be achieved with a high-dose supplementation of vitamin D.

The aim of this study is to examine the effect of vitamin D supplementation on exercise performance in wheelchair athletes with vitamin D deficiency . All participants with a vitamin D deficiency are assigned to the intervention group and treated with 6000 IU of vitamin D3 daily over a period of 12 weeks. All participants who have a normal vitamin D level will receive placebo treatment (control group). The physical performance is measured three times at baseline, after six weeks and 12 weeks. The measurements include a Wingate and a dynamometer test.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11
• Study First Submitted: 2015-11-24
• Study First Submitted QC: 2015-12-01
• Study First Posted: 2015-12-03
• Primary Completion: 2016-07
• Study Completion: 2016-08
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-21
• Last Update Posted: 2016-11-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• swiss elite wheelchair athlete
• 18 to 60 years
• male, healthy
• at least 2x45min sports a week

Exclusion Criteria

• participation in another study
• medication which influences performance
• respiratory and cardiovascular disease
• daily intake of >400IU Vitamin D
• parathyroid gland disease
• kidney insufficiency
• visit abroad below the 37th parallel latitude during study or shortly before

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Vitamin D	Vitamin D	alcohol-based (Ethanol 65%) Vitamin D3 (Vi-De 3®. WILD) solution 6000IU per day.
Placebo	Placebo	Same alcohol-based solution (Ethanol 65%) as intervention product but without cholecalciferol

Primary Outcome Measures

Name	Time	Method
maximum torque	delta change from pre to 12 weeks post supplementation	maximum torque measured with dynamometer
peak power	delta change from pre to 12 weeks post supplementation	peak power measured during wingate test

Secondary Outcome Measures

Name	Time	Method
Vitamin D serum level	12 weeks post supplementation	measured with venous blood sample
Count of injuries	12 weeks post supplementation	DASH questionaire

Trial Locations

Locations (1)

Swiss Paraplegic Centre; 🇨🇭 Nottwil, Lucerne, Switzerland