Effect of Vitamin D3 Supplementation on Exercise Performance in Wheelchair Athletes.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- maximum torque
研究概览
简要总结
There is a high prevalence of vitamin D deficiency in Switzerland. In indoor-athletes as well as wheelchair users, vitamin D deficiency occurs even more often. It is well established that vitamin D deficiency has a negative effect on health. However, vitamin D supplementation in individuals with a vitamin D deficiency has a positive effect on muscle performance. In recently published studies with able-bodied subjects, it has been shown that a normal vitamin D level (>75nmol/L) can only be achieved with a high-dose supplementation of vitamin D.
The aim of this study is to examine the effect of vitamin D supplementation on exercise performance in wheelchair athletes with vitamin D deficiency . All participants with a vitamin D deficiency are assigned to the intervention group and treated with 6000 IU of vitamin D3 daily over a period of 12 weeks. All participants who have a normal vitamin D level will receive placebo treatment (control group). The physical performance is measured three times at baseline, after six weeks and 12 weeks. The measurements include a Wingate and a dynamometer test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •swiss elite wheelchair athlete
- •18 to 60 years
- •male, healthy
- •at least 2x45min sports a week
排除标准
- •participation in another study
- •medication which influences performance
- •respiratory and cardiovascular disease
- •daily intake of >400IU Vitamin D
- •parathyroid gland disease
- •kidney insufficiency
- •visit abroad below the 37th parallel latitude during study or shortly before
结局指标
主要结局
maximum torque
时间窗: delta change from pre to 12 weeks post supplementation
maximum torque measured with dynamometer
peak power
时间窗: delta change from pre to 12 weeks post supplementation
peak power measured during wingate test
次要结局
- Vitamin D serum level(12 weeks post supplementation)
- Count of injuries(12 weeks post supplementation)
