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临床试验/NCT02621320
NCT02621320已完成不适用

Effect of Vitamin D3 Supplementation on Exercise Performance in Wheelchair Athletes.

Swiss Paraplegic Research, Nottwil2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2015年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20
试验地点
2
主要终点
maximum torque

研究概览

简要总结

There is a high prevalence of vitamin D deficiency in Switzerland. In indoor-athletes as well as wheelchair users, vitamin D deficiency occurs even more often. It is well established that vitamin D deficiency has a negative effect on health. However, vitamin D supplementation in individuals with a vitamin D deficiency has a positive effect on muscle performance. In recently published studies with able-bodied subjects, it has been shown that a normal vitamin D level (>75nmol/L) can only be achieved with a high-dose supplementation of vitamin D.

The aim of this study is to examine the effect of vitamin D supplementation on exercise performance in wheelchair athletes with vitamin D deficiency . All participants with a vitamin D deficiency are assigned to the intervention group and treated with 6000 IU of vitamin D3 daily over a period of 12 weeks. All participants who have a normal vitamin D level will receive placebo treatment (control group). The physical performance is measured three times at baseline, after six weeks and 12 weeks. The measurements include a Wingate and a dynamometer test.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • swiss elite wheelchair athlete
  • 18 to 60 years
  • male, healthy
  • at least 2x45min sports a week

排除标准

  • participation in another study
  • medication which influences performance
  • respiratory and cardiovascular disease
  • daily intake of >400IU Vitamin D
  • parathyroid gland disease
  • kidney insufficiency
  • visit abroad below the 37th parallel latitude during study or shortly before

结局指标

主要结局

maximum torque

时间窗: delta change from pre to 12 weeks post supplementation

maximum torque measured with dynamometer

peak power

时间窗: delta change from pre to 12 weeks post supplementation

peak power measured during wingate test

次要结局

  • Vitamin D serum level(12 weeks post supplementation)
  • Count of injuries(12 weeks post supplementation)

研究者

发起方
Swiss Paraplegic Research, Nottwil
申办方类型
Network
责任方
Sponsor

研究点 (2)

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