The EXPLORE MG Registry for Myasthenia Gravis

Recruiting

• Conditions: Myasthenia Gravis
• Interventions: Other: Blood Sample Draw

• Registration Number: NCT03792659
• Lead Sponsor: Yale University

Brief Summary

The purpose of this study is to create a Yale University Department of Neurology Myasthenia Gravis (MG) registry that will be used for current and future research projects involving the study of Myasthenia Gravis.

Detailed Description

This registry will allow for the research of several mechanisms of Myasthenia Gravis (MG) by studying peripheral blood, stool, disease status and course, and treatment of subjects with MG. The EXPLORE-MG Registry focuses on varied aspects of MG such as disease management, health care utilization, health costs, disease characteristics, and diagnostic tools. As such, it will aid in a broader understanding of MG, while providing a registry from which questions about the disease may be better answered.

Study Timeline

• Study Start: 2016-03-30
• Study First Submitted: 2019-01-02
• Study First Submitted QC: 2019-01-02
• Study First Posted: 2019-01-03
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-21
• Last Update Posted: 2024-10-22
• Primary Completion: 2026-09-30
• Study Completion: 2026-10-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• Adult patients diagnosed with Myasthenia Gravis presenting to the Yale Department of Neurology for clinical care or research interventions will be invited to donate their biological specimens/clinical data.

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Exclusion Criteria

• Failure to meet the Inclusion Criteria.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Neurological Outpatients	Blood Sample Draw	Participants in this group will be recruited from the outpatient clinical population at the Yale University Department of Neurology. Treating physicians will make the initial determination of patients' potential eligibility to participate in the study.

Primary Outcome Measures

Name	Time	Method
The number of successful blood draws will be reported at the conclusion of the sample collection	8 years	Successful Collection of Blood

Secondary Outcome Measures

Name	Time	Method
The number of stool samples collected will be reported at the conclusion of the sample	8 years	Count of Stool Samples

Trial Locations

Locations (1)

Yale-New Haven Hospital; 🇺🇸 New Haven, Connecticut, United States