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Clinical Trials/NCT03220555
NCT03220555
Completed
N/A

Efficacy of a Cold, Vibration, and Distraction Based Medical Device on the Prevention of Health Care Induced Pediatric Pain: a Comparative, Controlled, Randomized and Multicentric Study

Nantes University Hospital3 sites in 1 country220 target enrollmentOctober 4, 2017

Overview

Phase
N/A
Intervention
Buzzy® device
Conditions
Intravenous Injections
Sponsor
Nantes University Hospital
Enrollment
220
Locations
3
Primary Endpoint
Faces Pain Scale revised (FPS-r) for children
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

In vaccination centers, venipunctures and vaccinations are sources of pain and anxiety in pediatric patients. Prior painful experiences can reduce the acceptance of later health care, hence making it more difficult for both patients and nurses.

The topical anesthetic cream (lidocaine, prilocaine) and the non-pharmacological (distraction and relaxation) interventions which are usually used for prevention of procedural pain impose certain constraints on families and on vaccination centers.

A distraction and local anesthesia (cold and vibration) based medical device (Buzzy®) could overcome these constraints and could be an interesting alternative for healthcare management in vaccination centers and, in a broader perspective, in other medical services.

Research on this device has been scarce to date. Three of them have shown an efficacy of Buzzy® in comparison to the absence of prevention of vaccination and venipuncture induced pain. An ongoing study will assess the Buzzy® device in comparison to a topical anesthetic cream, but will be set in an emergency department context. To date, no study has compared Buzzy® to topical anesthetic cream on healthy children in a vaccination center.

The research team has formulated the following hypothesis: the Buzzy® device will allow to get a not lower or an equivalent level of pain compared to the level of pain obtained with the usual topical anesthetic cream. The aim of this study is to evaluate the efficacy of the device Buzzy® on vaccination and venipuncture induced pain in a vaccination center.

Registry
clinicaltrials.gov
Start Date
October 4, 2017
End Date
September 14, 2018
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Any child who:
  • requires a venipuncture or a vaccination in a vaccination center
  • is 4 to 15 years old
  • is affiliated to the public social security
  • speaks French or is assisted by an translator in the language of the child
  • has given his oral consent and whose parents have given it

Exclusion Criteria

  • Any child who:
  • suffers from sickle cell anemia
  • has a contraindication to use lidocaine patch
  • requires a Bacille de Calmette et Guérin (BCG) vaccine or tuberculin test
  • takes part in another research
  • has already participated to this study for another nursing care.
  • refused to participate or whose parents refused
  • has neurological or psychiatric disorders
  • has a nerve damage or an abrasion of the skin in terms of puncture or injection area.
  • under trusteeship or guardianship (unaccompanied foreign minors).

Arms & Interventions

Buzzy® device

Just before the vaccination or venipuncture the device will be applied on the selected site during 30 seconds and then it will be moved 5 cm above the selected site to make the injection or the puncture. The child will choose if he wants to use the cooling system.

Intervention: Buzzy® device

EMLAPATCH (lidocaine, prilocaine)

The patch will be applied during 1 hour to 1 hour and half before the vaccination or venipuncture, on the selected site. After 1 hour to 1 hour and half, it will be removed and the injection or the puncture will be made on the selected site.

Intervention: EMLAPATCH (lidocaine, prilocaine)

Outcomes

Primary Outcomes

Faces Pain Scale revised (FPS-r) for children

Time Frame: Day 0

Pain will be assessed by child using the FPS-r. FPS-r is a tool which has been validated and has been shown to be reliable in intercultural children and adolescents population (4 to 17 years).

Secondary Outcomes

  • Faces Pain Scale revised (FPS-r) for parents(Day 0)
  • Differential cost of the two strategies compared to the differential pain(Day 0)

Study Sites (3)

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