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Dexmedetomidine for Sedation Undergoing Bronchoscopy

Conditions
Safety Issues
Interventions
Procedure: bronchoscopy
Registration Number
NCT04169685
Lead Sponsor
Kaohsiung Medical University
Brief Summary

Several sedatives or analgesics can be used to achieve appropriate levels of sedation for endoscopic procedures. Dexmedetomide is notable for providing sedation without respiratory depression. We hypothesized dexmedetomide is more suitable for sedation of bronchoscopy than other sedative drugs.

Detailed Description

A retrospective chart review was conducted. All patients undergoing flexible bronchoscopy with moderate sedation were enrolled.The primary analysis outcome was safety profile during procedure included incidence of procedure interruption, incidence of snoring and observed apnea, transient hypoxemia and hypotension. The secondary outcome was measured by recovery profile (awake and ambulation time).

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
80
Inclusion Criteria
  • sedation undergoing flexible bronchoscopy
Exclusion Criteria
  • without sedation undergoing flexible bronchoscopy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
without dexmedetomidinebronchoscopyDrugs provided moderate sedation during procedure without dexmedetomidine
with dexmedetomidinebronchoscopyDrugs provided moderate sedation during procedure including dexmedetomidine
Primary Outcome Measures
NameTimeMethod
safety profile during procedureduring procedure

Incidence of procedure interruption, incidence of snoring and observed apnea, transient hypoxemia and hypotension

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Kaohsiung Medical University Hospital

🇨🇳

Kaohsiung, Taiwan

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