Comparison of Dexmedetomidine and Propofol for Sedation in Adult Patients Undergoing Flexible Bronchoscopy -A Retrospective Review
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Safety Issues
- Sponsor
- Kaohsiung Medical University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- safety profile during procedure
- Last Updated
- 6 years ago
Overview
Brief Summary
Several sedatives or analgesics can be used to achieve appropriate levels of sedation for endoscopic procedures. Dexmedetomide is notable for providing sedation without respiratory depression. We hypothesized dexmedetomide is more suitable for sedation of bronchoscopy than other sedative drugs.
Detailed Description
A retrospective chart review was conducted. All patients undergoing flexible bronchoscopy with moderate sedation were enrolled.The primary analysis outcome was safety profile during procedure included incidence of procedure interruption, incidence of snoring and observed apnea, transient hypoxemia and hypotension. The secondary outcome was measured by recovery profile (awake and ambulation time).
Investigators
Sheng-Hua Wu
MD
Kaohsiung Medical University
Eligibility Criteria
Inclusion Criteria
- •sedation undergoing flexible bronchoscopy
Exclusion Criteria
- •without sedation undergoing flexible bronchoscopy
Outcomes
Primary Outcomes
safety profile during procedure
Time Frame: during procedure
Incidence of procedure interruption, incidence of snoring and observed apnea, transient hypoxemia and hypotension