Gait Retraining to Reduce Knee Osteoarthritis Pain

Phase 1

Completed

• Conditions: Osteoarthritis, Knee
• Interventions: Behavioral: Gait retraining

• Registration Number: NCT01397981
• Lead Sponsor: Stanford University

Brief Summary

The purpose of this study is to determine how well people can be trained to produce new and different movements through the use of haptic feedback. One particular application is retraining individuals to walk differently in order to reduce knee joint loads to prevent or treat knee osteoarthritis as an alternative to surgical treatments.

Detailed Description

During the movement retraining session, you be given different combinations of haptic, visual, and auditory feedback in order to inform you on desired movement changes. This will take place at the Human Performance Laboratory at Stanford University. Motion analysis will be done while you perform movement activities (such as locomotion).

Prior to performing these movement tasks the investigators will attach reflective markers to your body using tape, pre-wrap and/or ace bandages. The investigators will record motion of your body's movements using infrared cameras which capture anatomical data from the reflective markers on your body.

The investigators will provide you with feedback to inform you of desired movement modifications. Haptic feedback devices such as vibration motors and skin stretch devices will be attached to your body via velcro straps and will be used to give "touch" feedback. There will be a computer monitor in front of you during testing to provide visual feedback. Sounds will be played using speakers near the testing area to provide auditory feedback.

The time needed for set up and performance of the above set of tests is approximately 90 minutes. You will be performing walking and other movements for only a small part of that time. The rest of the time will be spent preparing you for the experiment. After the investigators examine your movement data, if some of the data appear inaccurate or the investigators are unable to process the data, the investigators may ask you to repeat the movement analysis at a later time.

Study Timeline

• Study Start: 2011-07
• Study First Submitted: 2011-07-18
• Study First Submitted QC: 2011-07-19
• Study First Posted: 2011-07-20
• Primary Completion: 2012-04
• Study Completion: 2012-11
• Status Verified: 2013-03
• Last Update Submitted: 2013-03-05
• Last Update Posted: 2013-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Symptoms of medial compartment pain during the previous 6 weeks
• Radiographic evidence (AP X-ray) of medial compartment knee osteoarthritis (KL score of 3 or less)
• Ability to walk unaided for 25 minutes without rest
• Age > 18

Read More

Exclusion Criteria

• BMI > 30
• Previous injury or surgery on foot, ankle, knee, hip, or back inhibiting ability to adopt different walking gait
• Use of shoe insert or hinged knee brace
• Corticosteroid injection within the previous 6 weeks
• Age > 80

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Walking modification	Gait retraining	Changing kinematics for walking

Primary Outcome Measures

Name	Time	Method
Measure: Knee pain and function	four weeks	Knee pain and function will be assessed through the standardized KOOS survey

Secondary Outcome Measures

Name	Time	Method
Learning retention, knee adduction moment	four weeks	Learning retention of gait kinematics and knee joint loading including the knee adduction moment will be measured through motion capture and ground reaction force plates

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Stanford, California, United States