跳至主要内容
临床试验/NCT06023251
NCT06023251招募中不适用

Does the Use of Supplemental Parenteral/Enteral Nutrition and/or Oral Nutrition Supplements Guided by Indirect Calorimetry Combined With Standard of Care Increases Energy Feeding Adequacy in Patients Who Survived Critical Illness?

Universitair Ziekenhuis Brussel1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年10月4日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
100
试验地点
1
主要终点
Nutrition Adequacy

研究概览

简要总结

The objective is to increase caloric adequacy in patients who survived critical illness and are admitted to the ward by the use of a pro-active inclusive nutritional strategy including supplemental parenteral and/or enteral nutrition and/or oral nutritional supplements guided by indirect calorimetry.

This enables the investigators to address, within a clinical/scientific context, a recently demonstrated but until now relatively neglected 'dark side' of patient care at UZ Brussel, comparable to limited global evidence : iatrogenic malnutrition of ICU survivors. The use of a newly developed clinical pathway and nutrition strategy (oral, enteral and parenteral) led by a single SPoC (Single Point of Contact) for patients surviving intensive care will have a clear objective: to address the nutritional deficit in all patients.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult ≥ 18 years
  • ICU stay ≥ 7 days
  • Ward stay ≥ 3 days
  • Nutritional therapy not restricted
  • Heterogeneous diseases

排除标准

  • Patients < 18 years
  • ICU < 7 days
  • Ward stay < 3 days
  • Advanced Care Planning with impact on nutritional therapy
  • Patients with palliative care
  • Metabolic derangements such as metabolic diseases
  • Pregnancy

结局指标

主要结局

Nutrition Adequacy

时间窗: The adequacy will be calculated over the entire ward stay: from date of inclusion till 28 days later or death from any cause, whichever came first.

Increase of caloric adequacy (from 58 to 80%) and protein adequacy (from 52 to 80%) in ICU survivors

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Elisabeth De Waele

Head of Department

Universitair Ziekenhuis Brussel

研究点 (1)

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