Improving Nutritional Adequacy of ICU Survivors in a Prospective Interventional Way: the Bright Side Study

Not Applicable

Recruiting

• Conditions: Malnutrition

• Registration Number: NCT06023251
• Lead Sponsor: Universitair Ziekenhuis Brussel

Brief Summary

The objective is to increase caloric adequacy in patients who survived critical illness and are admitted to the ward by the use of a pro-active inclusive nutritional strategy including supplemental parenteral and/or enteral nutrition and/or oral nutritional supplements guided by indirect calorimetry.

This enables the investigators to address, within a clinical/scientific context, a recently demonstrated but until now relatively neglected 'dark side' of patient care at UZ Brussel, comparable to limited global evidence : iatrogenic malnutrition of ICU survivors. The use of a newly developed clinical pathway and nutrition strategy (oral, enteral and parenteral) led by a single SPoC (Single Point of Contact) for patients surviving intensive care will have a clear objective: to address the nutritional deficit in all patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-18
• Study First Submitted QC: 2023-09-01
• Study First Posted: 2023-09-05
• Study Start: 2023-10-04
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-22
• Last Update Posted: 2024-03-26
• Primary Completion: 2026-08-31
• Study Completion: 2026-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Adult ≥ 18 years
• ICU stay ≥ 7 days
• Ward stay ≥ 3 days
• Nutritional therapy not restricted
• Heterogeneous diseases

Exclusion Criteria

• Patients < 18 years
• ICU < 7 days
• Ward stay < 3 days
• Advanced Care Planning with impact on nutritional therapy
• Patients with palliative care
• Metabolic derangements such as metabolic diseases
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Nutrition Adequacy	The adequacy will be calculated over the entire ward stay: from date of inclusion till 28 days later or death from any cause, whichever came first.	Increase of caloric adequacy (from 58 to 80%) and protein adequacy (from 52 to 80%) in ICU survivors

Trial Locations

Locations (1)

UZ Brussel; 🇧🇪 Brussels, Belgium