Improving Nutritional Adequacy of ICU Survivors in a Prospective Interventional Way: the Bright Side Study

Not Applicable

Recruiting

• Conditions: Malnutrition
• Interventions: Other: Clinical Nutrition

• Registration Number: NCT06023251
• Lead Sponsor: Universitair Ziekenhuis Brussel

Brief Summary

The objective is to increase caloric adequacy in patients who survived critical illness and are admitted to the ward by the use of a pro-active inclusive nutritional strategy including supplemental parenteral and/or enteral nutrition and/or oral nutritional supplements guided by indirect calorimetry.

This enables the investigators to address, within a clinical/scientific context, a recently demonstrated but until now relatively neglected 'dark side' of patient care at UZ Brussel, comparable to limited global evidence : iatrogenic malnutrition of ICU survivors. The use of a newly developed clinical pathway and nutrition strategy (oral, enteral and parenteral) led by a single SPoC (Single Point of Contact) for patients surviving intensive care will have a clear objective: to address the nutritional deficit in all patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-18
• Study First Submitted QC: 2023-09-01
• Study First Posted: 2023-09-05
• Study Start: 2023-10-04
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-22
• Last Update Posted: 2024-03-26
• Primary Completion: 2026-08-31
• Study Completion: 2026-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Adult ≥ 18 years
• ICU stay ≥ 7 days
• Ward stay ≥ 3 days
• Nutritional therapy not restricted
• Heterogeneous diseases

Exclusion Criteria

• Patients < 18 years
• ICU < 7 days
• Ward stay < 3 days
• Advanced Care Planning with impact on nutritional therapy
• Patients with palliative care
• Metabolic derangements such as metabolic diseases
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Cohort	Clinical Nutrition	oral food, enteral nutrition, parenteral nutrition

Primary Outcome Measures

Name	Time	Method
Nutrition Adequacy	The adequacy will be calculated over the entire ward stay: from date of inclusion till 28 days later or death from any cause, whichever came first.	Increase of caloric adequacy (from 58 to 80%) and protein adequacy (from 52 to 80%) in ICU survivors

Trial Locations

Locations (1)

UZ Brussel; 🇧🇪 Brussels, Belgium