Children With Fever and Respiratory Symptoms at Out-of-hours Services in Norway
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 401
- 主要终点
- Antibiotic prescription rate
研究概览
简要总结
Viral self-limiting infections in respiratory organs among children are common in primary care. Serious infections have low prevalence and are challenging to distinguish from self-limiting infections.
Prescription of antibiotics in primary care is still high but stable since 2009 in Norway, and 90% of all antibiotics are prescribed in primary care.
C-reactive protein (CRP) has been especially popular in Norway for point-of-care testing in primary care, but its role in ruling-out serious infections and the cut-off value for prescribing antibiotics has been discussed a lot.
The aim of this study is to identify if pretesting with CRP of all children 0-6 year with fever or respiratory symptoms at Out-of-Hours Services will affect the prescription of antibiotics and the referral to hospital for children.
详细描述
Design: A randomized controlled observational study including children 0-6 year with fever and/or respiratory symptoms at 4 different Out-of-hour Services and at 1 Emergency Children Department Clinic at a hospital (open clinic). The data consist of clinical data and anamnestic information from a nurse at OOH-service collected before the consultation, the doctor's journal and a questionnaire to parents before the consultation and 1 week after the consultation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children 0-6 years with fever and/or respiratory symptoms
排除标准
- •Children older than 6 years with other conditions
结局指标
主要结局
Antibiotic prescription rate
时间窗: 24 hours
Number of participants prescribed antibiotics
次要结局
- Rate of side-effects of antibiotics(7 days)
- Duration of illness(7 days)
- Hospitalization rate(24 hours)