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Effectiveness of a reduced dose of ready-to-use therapeutic food (RUTF) in the management of uncomplicated severe acute malnutrition (SAM)

Not Applicable
Completed
Conditions
Severe acute malnutrition without medical complications
Nutritional, Metabolic, Endocrine
Registration Number
ISRCTN15258669
Lead Sponsor
Action Against Hunger
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
1000
Inclusion Criteria

1. Children aged 6 to 59 months
2. Only one child per sibling included in the study
3. Severe acute malnutrition (weight-height index <-3 Z-score and/or mid-upper arm circumference <115 mm and/or bilateral edema (+: edema localized to the lower limbs; ++: edema localized to the lower and upper limbs)
4. Without medical complications
5. With conclusive appetite test
6. Living in the selected health zone
7. Consent to participate in the study (informed consent)
8. When there are several participants in the same sibling, only the first to be included in the study will be randomized. The others will automatically be included in the same group as the first one without being randomized and will not be taken into account in the analyses

Exclusion Criteria

1. Inconclusive appetite test
2. Siblings of SAM children: any SAM child whose brother or sister (same father, same mother) is already enrolled in the study. Be careful, he/she will have to receive the same dose as his/her brother or sister outside the study in order not to create a bias with different doses within the same family
3. Declared allergy to peanut and/or milk
4. Previously treated for SAM in the past 6 months, including readmissions after program dropout, relapses and medical transfers
5. Malformation or disability or chronic pathologies that can affect food intake, such as cleft palate, cerebral palsy, trisomy 2, sickle cell anemia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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