Evaluation of the effectiveness of low-dose ketamine (Sub dissociative) with dexmedetomidine in controlling pain in patients with limb trauma referred to emergency department

Phase 3

• Conditions: G89.11; Pain management of limb trauma in emergency department.; Acute pain due to trauma

• Registration Number: IRCT20220120053770N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 258

Inclusion Criteria

Adult patients (older than 18 years old)
gave pain more than five points
limb trauma pain
obtaining the informed consent

Exclusion Criteria

Pain score =5 Pregnancy and post-partum women Altered mental status Allergy to ketamine or fentanyl Body weight = 46 kg or = 115 Unstable vital signs: BP= 90 mmHg or = 180 mmHg , PR=150 or =50 bits/min , RR=10 or =30 History of recent head or eye trauma History of Siesure History of elevated ICP Chronic pain Renal or hepatic failure Substance or alcohol abuse Documented psychiatric disorders Opium addiction Recent use of narcotic analgesics

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain numerical rating scale. Timepoint: Intervals of 5, 10, 15, 30 minutes. Method of measurement: requires the patient to rate their pain (0–10) where 0 is no pain and 10 is the worst pain imaginable.