A study on the effect of early walking after endonasal surgery on recovery among patients with pituitary region tumors at PGIMER, 2024–2026.

Phase 2

Not yet recruiting

Conditions: Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system, (2) ICD-10 Condition: G938||Other specified disorders of brain, (3) ICD-10 Condition: G938||Other specified disorders of brain,

Brief Summary: This randomized controlled trial aims to evaluate the effectiveness of early postoperative ambulation on clinical outcomes and quality of life in patients undergoing endonasal surgery for pituitary region tumors at PGIMER, Chandigarh. A total of 80 adult patients will be selected and randomly allocated using a computer-generated random number table with allocation concealment, assigning 40 participants each to the experimental (early ambulation + routine care) and control (routine care only) groups. Inclusion criteria include adult patients undergoing endonasal surgery who are ambulatory and able to begin walking within 12 hours post-lumbar puncture. Outcome variables include postoperative complications, duration of hospital stay, headache severity, sinus-related quality of life (SNOT-22), and WHOQOL scores. Data will be collected through interviews, clinical records, and standardized tools. Follow-ups will be done on postoperative days 1 to 3 and at discharge, with a final assessment at one month post-surgery. Data will be analyzed using descriptive and inferential statistics. The findings will help support early ambulation practices to enhance recovery and improve the quality of life in neurosurgical patients.

Recruitment & Eligibility

Inclusion Criteria

Adult patients planned for endo nasal surgery for pituitary region tumor who are ambulatory without support before surgery.
Patients willing to participate in study.
Patients who undergo a lumbar puncture postoperatively will have early ambulation started after 12 hours of lumbar puncture.

Exclusion Criteria

Patients who are unconscious.
Patients who are intubated beyond 11am on post operative day 1.
Patients who are hemodynamically unstable, whose systolic blood pressure is less than 100 mm Hg. 4.Patients who have lumbar drain during surgery.

Primary Outcome Measures

Name	Time	Method
quality of life	at the end of 1 month after surgery

Secondary Outcome Measures

Name	Time	Method
clinical outcomes- 1. Headache	2. Post operative complications- CSF rhinorrhea, DVT and others

Locations (1): Nehru Hospital, PGIMER, Chandigarh
🇮🇳
Chandigarh, CHANDIGARH, India
Nehru Hospital, PGIMER, Chandigarh
🇮🇳Chandigarh, CHANDIGARH, India
Ms Rajveer Kaur
Principal investigator
7060480425
rajveerkaur5991@gmail.com