DRKS00025879Completed未知
Investigate the effects of a spermidine supplementation on immune system and inflammatory parameters in old and young adults - ImmuneAge-Study
Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DIfE)0 sites40 target enrollmentStarted: April 28, 2022Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Enrollment
- 40
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized controlled study
- Masking
- Blinded (masking used)
Eligibility Criteria
- Ages
- 25 Years to 90 Years (—)
- Sex
- All
Inclusion Criteria
- •Young adults: age: 25-40 years; BMI: 20-30 kg/m²; no chronic medication except for oral contraceptives;
- •Old adults: age: 70-90 years; BMI: 20-30 kg/m²;
- •No limitations in ‘’activities of daily living’’;
- •Subjects must be able to consent as defined by law.
Exclusion Criteria
- •Pregnancy/breastfeeding;
- •Existing or past immune diseases such as leukemia, lymphoma, malignant neoplasms affecting bone marrow and lymphatic system, HIV or AIDS;
- •Self-reported severe or active medical conditions such as arteriosclerosis, advanced cardiac or respiratory disease, such as chronic obstructive pulmonary disease (COPD; GOLD-Stadium =3 (Global Initiative for Chronic Obstructive Lung Disease”-classification)) or heart failure (NYHA =3 (New York Heart Association));
- •Self-reported neurological or mental impairment;
- •Self-reported severe liver, kidney, or metabolic disease, such as liver cirrhosis (Child Pugh Score =2) or kidney disease (Stadium =3);
- •Drug/medication/alcohol dependence;
- •Existing polyamine supplementation;
- •Known intolerances or allergies to wheat germ, gluten, or histamine.
Investigators
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