Surveillance of Pertussis cases in hospitalised babies
- Conditions
- Health Condition 1: J00-J99- Diseases of the respiratory systemHealth Condition 2: null- Hospitalised infants with clinical suspicion of pertussis
- Registration Number
- CTRI/2018/07/014911
- Lead Sponsor
- KEM Hospital Research Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
1. Age <1 year
2. Hospitalization in one of the study hospitals
3. Fulfilling the clinical criteria for Pertussis
4. Parent/ guardian of the child give written informed consent
Clinical criteria
Progressive cough, possibly paroxysmal, with coryza and no or minimal fever
PLUS one or more of the following symptoms or conditions:
1. Whoop
2. Apnea
3. Post-tussive emesis
4. Cyanosis
5. Seizure
6. Pneumonia
7. Worsening of symptoms at night
8. Increased white blood cell (WBC) count (>= 20,000 WBC per mcl with >= 10,000 lymphocytes per mcl)
9. Close exposure to an older child, adolescent or adult with prolonged afebrile cough illness.
10. Neonates and young infants ( <60 days) may present without cough and any one or more of the above symptoms without any obvious cause may be considered for suspicion of pertussis and inclusion as possible pertussis.
Parent/ guardian not agreeing for written informed consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber and proportion of hospitalized infants with laboratory confirmed pertussis amongst the all infants with clinical suspicion of pertussis.Timepoint: 12 Months
- Secondary Outcome Measures
Name Time Method Clinical characteristics and complications in infants with laboratory confirmed pertussisTimepoint: 12 months;Economic burden of pertussis on householdTimepoint: 12 months;Seasonality of the laboratory confirmed pertussisTimepoint: 12 months;Socio-demographic profiling of the laboratory confirmed pertussis casesTimepoint: 12 months