CTRI/2026/01/101243尚未招募3 期
Comparative study of intralesional triamcinolone acetonide injection and hyaluronidase with and without platelet rich plasma therapy in the treatment of keloids
Dr Baba saheb ambedkar hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年1月27日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
To compare the efficacy of intralesional triamcinolone acetonide injection with hyaluronidase and PRP vs intralesional triamcinolone acetonide injection with hyaluronidase in the treatment of keloids when given 3 weekly for 4 doses as assessed by mean Vancouver scar scale at 12 weeks follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Clinically diagnosed cases of localized keloid aged 18-60 years of either gender.
- •Patients with Vancouver scar score greater than or equal to 4.
排除标准
- •Pregnant or Lactating Women
- •Presence of infection (bacterial, viral, or fungal) at or around the keloid site.
- •History of allergy or hypersensitivity to triamcinolone acetonide, hyaluronidase and components of PRP preparation.
- •Patients with History of bleeding disorders (e.g., hemophilia, thrombocytopenia) and Use of anticoagulants or antiplatelet drugs that cannot be discontinued.
- •Patients with Immunocompromised States Including those with HIV/AIDS, on chemotherapy, or long-term immunosuppressive therapy
- •Prior intralesional steroid, hyaluronidase, PRP injections to the same keloid lesion within the last 3 months.
- •Current or recent (within 1 month) systemic corticosteroid or immunosuppressant therapy.
- •Chronic medical conditions that may affect healing like poorly controlled diabetes mellitus , chronic kidney disease and liver dysfunction or cirrhosis
- •Areas where assessment is difficult (e.g., scalp under thick hair, mucosal surfaces)
- •History of keloid excision in the past 3 months.
- •Patients with widespread keloidosis rather than isolated, well-defined keloid lesions.
- •Ear keloid.
研究者
Brinda K
Baba Saheb Ambedkar medical college and hospital
研究点 (1)
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