Studies of Pancreatic Islet Mass by Positron Emission Tomography (PET)

Completed

• Conditions: Type 1 Diabetes

• Registration Number: NCT01552811
• Lead Sponsor: Uppsala University Hospital

Brief Summary

This study investigates the hypothesis that differences in beta-cell mass in patients with diabetes and healthy individuals can be monitored by the positron emission tomography (PET) tracer \[11C\]5-hydroxytryptophane.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Study First Submitted: 2012-03-09
• Study First Submitted QC: 2012-03-12
• Study First Posted: 2012-03-13
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Status Verified: 2014-02
• Last Update Submitted: 2014-02-04
• Last Update Posted: 2014-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Adult patients with type 1 diabetes
• Adult, healthy controls

Exclusion Criteria

• Pregnancy
• Impaired renal function

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in pancreatic uptake of % injected dose (ID) [11]5-hydroxy tryptophan between healthy volunteers and patients with long-standing type 1 diabetes	To be measured at Positron emission tomography investigation for all study persons.

Trial Locations

Locations (1)

Uppsala University Hospital; 🇸🇪 Uppsala, Sweden