Future of Beta Cells in Adults With Genetic Abnormality Behind Neonatal Diabetes

• Conditions: Diabetes

• Registration Number: NCT02072551
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The main objective of this study is to evaluate Beta cells in patients with a neonotal diabetes linked to a genetic abnormality Metabolic caracteristics will described using a transversal cohort study.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-12
• Study First Submitted: 2013-11-04
• Study First Submitted QC: 2014-02-25
• Study First Posted: 2014-02-26
• Status Verified: 2016-04
• Last Update Submitted: 2016-04-15
• Last Update Posted: 2016-04-18
• Primary Completion: 2016-12
• Study Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Age : 18 à 65 year
• diabetic patient with a neonatal diabetis (before 1 year old) and need for insuline or patient with a relative having neonatal diabetis

Exclusion Criteria

Diabète induit (médicaments - ex corticoïdes) ou syndromique

• infection
• cancer
• pegnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean insulin secretion output	Week after inclusion

Secondary Outcome Measures

Name	Time	Method
sensitivity to insulin	during hospitalisation (3 days)
insulin secretion outout after arginine perfusion	during hospitalisation (3 days)
glucago secretion output	during hospitalisation (3 days)

Trial Locations

Locations (1)

Hopital Siant-louis; 🇫🇷 Paris, France