Effect of Zinc in improvement of Aphthous
- Conditions
- Recurrent Aphthous Stomoatitis.Recurrent oral aphthae
- Registration Number
- IRCT20151109024975N9
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 46
Individuals with adequate knowledge and literacy
Age group is 16 to 45 years old
Aphthous diagnostic criteria
Ability to fill out the consent form legally
Individuals with major recurrent aphthous stomatitis & herpetic form
Patients who had aphthous lesions in other areas than Labial & Buccal mucosa
Patients with systemic disease during last month
Patients with Denture
Patients consuming antibiotics
Patients with pregnancy
Individuals with poor oral hygiene
Individuals who are not capable of receiving Zinc sulfate mucoadhesive
Individuals who have syndromes which Aphthous ulcers are one the manifestations, like Behcet's syndrome
Individuals who are prescribed a non-Zinc drug for Aphthous improvement
Smoking Individuals
Individuals who consume Immunosuppressive drug during last month
Individuals who couldn't resume the study according to social or personal issues
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diameter of eritmathous halo. Timepoint: Zero (before entering the study); third; fifth and seventh days. Method of measurement: Metal caliber.
- Secondary Outcome Measures
Name Time Method Period of improvement. Timepoint: Zero (before entering the study); third; fifth and seventh days. Method of measurement: Visual Analogue Scale Questionnaire.