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Clinical Trials/ISRCTN12738881
ISRCTN12738881
Active, not recruiting
未知

The effect of A-PRF on preventing systemic inflammation: A pilot randomized controlled clinical trial

niversity of Santiago de Compostela0 sites20 target enrollmentDecember 16, 2020

Overview

Phase
未知
Intervention
Not specified
Conditions
Systemic acute inflammatory response after wisdom tooth removal in otherwise healthy patients
Sponsor
niversity of Santiago de Compostela
Enrollment
20
Status
Active, not recruiting
Last Updated
5 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 16, 2020
End Date
April 30, 2021
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Santiago de Compostela

Eligibility Criteria

Inclusion Criteria

  • 1\. Two unilateral fully impacted mandibular third molars which have the same degree of surgical difficulty comparing one side with the other
  • 2\. Healthy patients without significant medical diseases or a history of bleeding problems
  • 3\. Adequate level of plaque control (plaque index (PI) \<15%)
  • 4\. Non\-smokers patients
  • 5\. Able to give written consent

Exclusion Criteria

  • 1\. Younger than 18 years old or older than 65 years old
  • 2\. Females who were pregnant or lactating
  • 3\. Females using contraceptive methods
  • 4\. Had any reported systemic illness
  • 5\. Had chronic use of any medication within 30 d prior to the study inclusion
  • 6\. Affected by periodontitis (Tonetti, Greenwell, \& Kornman, 2018\)
  • 7\. Signs of pericoronitis
  • 8\. Removable upper and/or lower partial dentures
  • 9\. Had periapical and periradicular radiolucencies that were detected on X\-rays

Outcomes

Primary Outcomes

Not specified

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