Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis

Not Applicable

Completed

• Conditions: Chorioamnionitis
• Interventions: Drug: gentamicin

• Registration Number: NCT00185991
• Lead Sponsor: Stanford University

Brief Summary

To compare once daily versus 8 hour dosing of gentamicin for the treatment of chorioamnionitis.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-06
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Study First Posted: 2005-09-16
• Primary Completion: 2006-10
• Study Completion: 2010-02
• Status Verified: 2011-06
• Last Update Submitted: 2011-06-13
• Last Update Posted: 2011-06-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 126

Inclusion Criteria

• clinical diagnosis of chorioamnionitis

Exclusion Criteria

• maternal renal disease, intrauterine fetal death, allergy to gentamicin

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Once daily Gentamicin	gentamicin	-
Every eight hour Gentamicin	gentamicin	-

Primary Outcome Measures

Name	Time	Method
Afebrile at 24 hours and no endometritis	24 hours after delivery

Secondary Outcome Measures

Name	Time	Method
Neonatal outcomes	Time of delivery to time of discharge

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Stanford, California, United States