Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement: a Randomized Controlled Clinical Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Measurement of alveolar bone volume
Study Overview
Brief Summary
Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Other
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 15 Years to 25 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Malocclusion that requires at least the extraction of maxillary first premolars, followed by canine retraction into the extraction site, such as Class I bimaxillary protrusion, and Class II division 1 cases.
- •Normal shape and structure of the maxillary canines, with no history of root canal treatment
Exclusion Criteria
- •Patients who underwent previous orthodontic treatment.
- •Patients currently receiving drug therapy, e.g. hormonal therapy and corticosteroids, as well as patients with chronic diseases.
- •Pregnancy and lactation.
Arms & Interventions
Low level laser therapy
Intervention: Low level laser therapy (Radiation)
Control
Intervention: without beam emission (Other)
Outcomes
Primary Outcomes
Measurement of alveolar bone volume
Time Frame: 3 months
From CBCT scans, bone volume in areas of the maxillary alveolar process between the canine and lateral incisor, and between the canine and second premolar will be measured
Measurement of buccal bone thickness
Time Frame: 3 months
buccal bone thickness will be measured from the CBCT scans. Three points will be measured from the buccal bone to the root, at the coronal, mid-root, and apical level
Measurement of alveolar bone microstructure
Time Frame: 3 months
From the CBCT scans, the maxillary alveolar process between the canine and lateral incisor, and between the canine and second premolar will be examined. Bone microstructures will be measured and calculated with a dedicated software.
Measurement of alveolar bone density
Time Frame: 3 months
Bone density will be measured from cone beam computed tomography (CBCT) scans at 2 different locations on each side of the upper arch; between the canine and lateral incisor, and between the canine and second premolar. Bone density will be measured using Hounsfield Units (HU).
Measurement of bone Microstructure
Time Frame: 3 months
Using the collected CBCT scans, the region of interest will be selected within the maxillary alveolar process, and fractal dimension analysis will be performed using a special software.
Secondary Outcomes
No secondary outcomes reported
Investigators
Nourhan M.Aly
Assistant Lecturer of Dental Public Health
University of Alexandria