Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement

Not Applicable

Completed

• Conditions: Low Level Laser Therapy; Canine Retraction; Orthodontic Tooth Movement
• Interventions: Radiation: Low level laser therapy; Other: without beam emission

• Registration Number: NCT05811728
• Lead Sponsor: Nourhan M.Aly

Brief Summary

Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-25
• Study First Submitted: 2023-04-01
• Study First Submitted QC: 2023-04-12
• Study First Posted: 2023-04-13
• Primary Completion: 2023-08-31
• Study Completion: 2023-08-31
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-17
• Last Update Posted: 2023-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Malocclusion that requires at least the extraction of maxillary first premolars, followed by canine retraction into the extraction site, such as Class I bimaxillary protrusion, and Class II division 1 cases.
• Normal shape and structure of the maxillary canines, with no history of root canal treatment

Exclusion Criteria

• Patients who underwent previous orthodontic treatment.
• Patients currently receiving drug therapy, e.g. hormonal therapy and corticosteroids, as well as patients with chronic diseases.
• Pregnancy and lactation.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Low level laser therapy	Low level laser therapy	-
Control	without beam emission	-

Primary Outcome Measures

Name	Time	Method
Measurement of buccal bone thickness	3 months	buccal bone thickness will be measured from the CBCT scans. Three points will be measured from the buccal bone to the root, at the coronal, mid-root, and apical level
Measurement of alveolar bone microstructure	3 months	From the CBCT scans, the maxillary alveolar process between the canine and lateral incisor, and between the canine and second premolar will be examined. Bone microstructures will be measured and calculated with a dedicated software.
Measurement of alveolar bone density	3 months	Bone density will be measured from cone beam computed tomography (CBCT) scans at 2 different locations on each side of the upper arch; between the canine and lateral incisor, and between the canine and second premolar. Bone density will be measured using Hounsfield Units (HU).
Measurement of alveolar bone volume	3 months	From CBCT scans, bone volume in areas of the maxillary alveolar process between the canine and lateral incisor, and between the canine and second premolar will be measured
Measurement of bone Microstructure	3 months	Using the collected CBCT scans, the region of interest will be selected within the maxillary alveolar process, and fractal dimension analysis will be performed using a special software.

Trial Locations

Locations (1)

Faculty of Dentistry, Alexandria University; 🇪🇬 Alexandria, Egypt