Comparing osteocalcin levels in GCF after surgical management of intrabony defects with and without i-PRF for assessment of periodontal regeneration– A Pilot study

Not Applicable

• Conditions: Health Condition 1: K053- Chronic periodontitis

• Registration Number: CTRI/2023/12/060963
• Lead Sponsor: Dr Shraddha Iyer

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients diagnosed with chronic periodontitis stage III or IV, grade A

2. Interdental clinical attachment loss (CAL) of > 5 mm, probing pocket depth (PPD) of > 5 mm

3. Paired intrabony defect of > 3mm depth (including two and three walled-defects)

4. Patients undergoing guided tissue regeneration of intrabony defect (Group A and Group B).

5. Patients who are ready to give informed consent for blood withdrawal and GCF collection, and willing to undergo treatment and follow-ups.

Exclusion Criteria

1. History of known systemic diseases like diabetes, hypertension, human immunodeficiency virus, bone disorders, immunosuppressive therapy, radiation therapy, cancer, or blood disorders.

2. Patients on medications known to affect the outcomes of periodontal therapy.

3. Patients who have undergone any surgical periodontal therapy in the preceding 6 months.

4. Pregnant or lactating mothers.

Use of tobacco in any form

Study & Design

• Study Type: Interventional
• Study Design: Not specified