The effectiveness of exercise on adults with high blood pressure resistant to drugs and with breath pauses during sleep
- Conditions
- Cardiovascular - HypertensionResistant hypertensionObstructive sleep apnoeaRespiratory - Sleep apnoeaPhysical Medicine / Rehabilitation - Physiotherapy
- Registration Number
- ACTRN12618001881224
- Lead Sponsor
- Suranga Dassanayake
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
24h ambulatory blood pressure above 130/85 mmHg
Prescribed three or more antihypertensive medications including a diuretic
ESS score above or equal to 9
Age between 18-60 years inclusive
All gender
Fit to participate in the 12-week physical exercise programme based on the Physical Activity Readiness Questionnaire (2017 PAR-Q +) of the American College of Sports Medicine (ACSM) and recommendation of a cardiologist.
Able to communicate and follow instructions in English
Individuals with systemic diseases, history of cardiovascular diseases (Myocardial infarction or Stroke) within 6 months and other severe heart conditions and with physical ailments, acute musculoskeletal injuries.
Not fit to exercise according to exercise readiness questionnaire and who are not recommended by the cardiologist
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The changes of 24-hour ambulatory blood pressure of population with true resistant hypertension and high risk of obstructive sleep apnoea.<br><br>This outcome will be assessed by 24 ambulatory blood pressure monitor (Holter monitor) worn for 24 h, the blood pressure cuff fitted on the non-dominant upper arm. (ABPM - 90207, Spacelabs, Snoqualmie, Washington, USA)<br>[Baseline and 12 weeks after intervention commencement.]
- Secondary Outcome Measures
Name Time Method