Survivorship of Patients post Long Intensive care stay, Exploration/Experience in a New Zealand cohort.

Not Applicable

Active, not recruiting

Conditions: Post Intensive Care Syndrome
disability
Recovery post critical illness
Other - Conditions of unknown or disputed aetiology (such as chronic fatigue syndrome/myalgic encephalomyelitis)
Mental Health - Other mental health disorders
Neurological - Other neurological disorders
Public Health - Health service research

Registration Number: ACTRN12621001335886

Lead Sponsor: niversity Of Otago, Wellington

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Active, not recruiting

Sex: All

Target Recruitment: 118

Inclusion Criteria

All patient participants will be adult ICU patients admitted to Wellington ICU who are > 18 years old, been in an ICU for seven or more consecutive days, or patients who were mechanical ventilated for >48 hours. Patients who have been in another New Zealand ICU/Critical Care Unit prior to retrieval to Wellington ICU will be included once both admissions = >7 days.

Mechanical Ventilation is defined as a positive pressure ventilation (PPV) mode via an Endotracheal, Nasotracheal or Tracheostomy tube. Patients who have been extubated from PPV for a period and then reintubated are also included if both periods of PPV exceed 72 hours.

Exclusion Criteria

Patients who are < 18 years old
•Non-English speakers
•Patients not expected to survive their hospital stay (deemed by ICU Senior Medical Officer (SMO) once inclusion criteria met).
•Patients in whom follow up would be challenging/impossible (e.g., prisoners, people who are homeless).
•Patients with pre-existing neuromuscular disorder (e.g., Muscular Dystrophy, Multiple Sclerosis, Myasthenia Gravis, Guillain Barre).
•Neurovascular/neurotrauma/status epilepticus.
•Patients who have hypoxic/ischemic brain injury/encephalopathy.
•Significant pre-existing psychiatric disease or intellectual disability such that the patient was mentally, cognitively, or functionally impaired prior to ICU admission.
•Patients with diagnosed neurodegenerative disease
•Patients with prior moderate to severe cognitive impairment (as recorded in the patient health records/medical notes).
•Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the trial, or may influence the result of the trial, or the participant’s ability to participate in the trial.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of participants who score 'mild', 'moderate' or 'severe' level of disability according to WHODAS 2.0 scores will be assessed as the primary composite outcome dichotomised into mild, moderate, severe level of disability:<br>The total score between 0 and 48, is then divided by 48 and multiplied by 100 to convert it to a percentage of maximum disability. <br>•No disability 0–4%<br>•Mild disability 5–24% <br>•Moderate disability 25–49% <br>•Severe disability 50–95% <br>•Complete disability 96–100%[ At 4-6 weeks, 6 months and 12 months post hospital discharge]

Secondary Outcome Measures