Comparative study on Efficacy and Adverse Effects of Ginger extractand loratadine for Treatment of Allergic rhinitis patients (Clinical Trial Phase III)

Center of Excellence on Applied Thai Traditional Medicine Research (CEATMR)0 个研究点目标入组 300 人开始时间: 2019年10月18日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1.. Patients have history of allergic rhinitis on the basis of â€œAllergic Rhinitis and its Impact on Asthmaâ€;itching and nasal obstruction, watery nasal discharge, sneezing, congestion
•2. Patients have moderate allergic rhinitis diagnosed by doctor with a minimum total nasal symptom score of 5 points
•3. Volunteers wish to participate in the research

•1. Patients have ginger allergy.
•2. Patients get serious side effects from loratadine.
•3. Patients have fever.
•4. Patients have respiratory disease such as tuberculosis, nasal polyps.
•5. Patients have history of disease: heart disease, kidney disease, liver disease, epilepsy, high blood pressure, severe asthma and gall Stone.
•6. Patients have higher than normal value in liver function and renal function.
•7. Patients are pregnant or breastfeeding.
•8. Immunocompromised patients
•9. Patients have taken anti-coagulant, anti-platelet aggregation medications, Macrolides(erythromycin, clarithromycin), Imidazole (ketoconazole, itraconazole, fluconazole), HIV protease inhibitors, Other drugs that inhibit the enzyme CYP450 (cimetidine, metronidazole, zafirlukast, SSRIs)
•10. Patients can not stop taking antihistamine or intranasal steroids for 1 week before trial.
•11. Communication problems especially listening and interview.
•12. The patient cannot be free from the research plan for 14 days.
•13. Those who are participating in another research project.

发起方

Center of Excellence on Applied Thai Traditional Medicine Research (CEATMR)