The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diameter in Laparotomic Gynecological Surgery
概览
- 阶段
- 不适用
- 干预措施
- The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
- 疾病 / 适应症
- Optic Nerve Sheath Diameter
- 发起方
- Bursa Yuksek Ihtisas Training and Research Hospital
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Optic Nerve Sheath Diamater
- 状态
- 已完成
- 最后更新
- 2个月前
概览
简要总结
Different amounts of anesthetic gas can be used in the obstetric gynecological surgery operations to be performed with open method. Researchers aimed to compare the effect of gas changes on intraocular nerve diameter by ultrasonography.
详细描述
A total of 80 patients who underwent laparotomic gynecological surgery were divided into two groups prospectively: high flow of 2 L/min and minimal flow of 0.5 L/min. Anesthesia was maintained with 50% oxygen-50% air at 2 L/min and desflurane at 1.1 MAC in Group 1 (n=40) and with 50% oxygen-50% air at 2 L/min and desflurane at 1.1 MAC in Group 2 (n=40). After 10-15 minutes, group 2 was administered minimal flow with 50-60% oxygen-40-50% air at 0.5 L/min and desflurane, and 10 minutes before the end of the surgery, the patients were switched to high flow with 50% oxygen-50% air at 2 L/min.
研究者
Anıl Onur
Principle İnvestigator
Bursa Yuksek Ihtisas Training and Research Hospital
入排标准
入选标准
- •Aged 18-65 years
- •Who underwent laparotomic gynecological surgery
排除标准
- •Patients with obstructive pulmonary disease
- •Patients with decompensated diabetes, those with a fasting period of more than 12 hours -Acute alcohol intoxication
- •Chronic alcohol use
- •Who refuse to participate in the study
- •Who are not cooperative, do not speak Turkish
- •Who had known eye disease (glaucoma, retinal detachment), had a previous history of eye surgery,
- •Increased intracranial pressure findings (intracranial lesion, previous cerebrovascular diseases
- •Body mass index of \> 40kg/m2
- •ASA \> III
研究组 & 干预措施
High Flow Anesthesia, Low Flow Anesthesia
. The patients were randomly allocated to one of the two groups of fresh gas flows using the closed-envelope technique: 2 L/min high flow and 0.5 L/min minimal flow. Group 1 (n = 40) was operated under high flow anesthesia with 50% O2 - 50% air at 2 L/min and desflurane at 1.1 MAC for the duration of the surgery. For anesthesia maintenance, Group 2 (n=40) was administered 50% oxygen - 50% air at 2 L/min and desflurane for 10-15 minutes. After reaching 1.1 MAC, it was switched to minimal flow with 50-60% oxygen- 40-50% air at 0.5 L/min and desflurane. 10 minutes before the end of the surgery, it was switched to high flow with 50% oxygen -50% air at 2 L/min.
干预措施: The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
Peroperetive Optic Nerve Sheath Diameter
Optic nerve sheath diameter measurements were performed by an experienced and the same anesthetist. In the measurements, the GE Healthcare Logiq e series USG device and 12-MHz linear probe were used. Longitudinal and transverse axis images were obtained on both eyelids while the patient was in the supine position. Measurements were taken 3 mm behind the optic nerve head
干预措施: The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
结局指标
主要结局
Optic Nerve Sheath Diamater
时间窗: 2 hours operation time
Optic nerve sheath diamater measurements of the patients were recorded before and during the surgery at specified time points (T0: awake, T1: High fresh gas flow after induction at the 10th min., T2: Inhalation anesthesia at the 30th min., T3: Inhalation anesthesia at the 60th min., T4: Inhalation anesthesia at the 90th min., T5: Before extubation).A typical optic nerve sheath is generally less than 5 mm in diameter, and diameters greater than 5.5 mm predict an ICP of ≥20 cm H2O with 100% sensitivity and specifity
次要结局
- Peroperative Complications(2 hours operation time)
- Postoperative Complications(postop 20 minutes)