Transjugular Intrahepatic Porto-systemic Shunt (TIPS) with Gore-tex(R) covered stent-graft versus endoscopic treatment for secondary prevention of gastro-esophageal variceal bleeding.

Erasmus MC, department of Radiology and Department of Gastro-enterology0 sites72 target enrollmentTBD

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: TIPS, endoscopic treatment, variceal bleeding(TIPS, endoscopische behandeling, varices bloedingen)
Sponsor: Erasmus MC, department of Radiology and Department of Gastro-enterology
Enrollment: 72
Status: Not yet recruiting
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sponsor

Erasmus MC, department of Radiology and Department of Gastro-enterology

•1\. Patients presenting with a first or second episode of esophageal or gastric variceal bleeding, as documented by endoscopy and meeting accepted diagnostic criteria;
•2\. Initial stabilization (absence of evidence of continued bleeding);
•3\. Informed consent;
•4\. Age \> 18 and \< 76 years

•1\. History of serious or refractory encephalopathy, unrelated to gastrointestinal bleeding;
•2\. History of significant heart failure (NYHA class III \& IV);
•3\. Portal hypertension due to other causes than liver disease (e.g. portal vein or splenic vein thrombosis);
•4\. Previous TIPS placement;
•5\. Advanced hepatocellular carcinoma;
•6\. Severely compromised liver function (Child\-Pugh score \>13\);
•7\. Sepsis and/or multiorgan failure