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Feasibility Study to Improve AF Outcomes Using a Digital Application for CV Risk Reduction

Not Applicable
Terminated
Conditions
Atrial Fibrillation
Interventions
Device: AF CARE
Behavioral: Usual Care
Registration Number
NCT04050982
Lead Sponsor
Stanford University
Brief Summary

The pilot portion of this study is to determine the feasibility of utilizing AF CARE to provide lifestyle modification support to patients with atrial fibrillation (AF).

The prospective, RCT portion of this study compare cardiovascular risk factors (CVRF), AF knowledge, AF Symptom Severity and Burden, and QOL between and within the wait list group and the AF CARE group at baseline, 3, 6, and 12 months.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
11
Inclusion Criteria
  1. BMI > 28 kg/m2 AND one additional CVRF using LS7
  2. Access and willingness to engage in digital technology
  3. Has a valid email address and a cell phone number
  4. Able to ambulate
  5. Able to speak/read English
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Exclusion Criteria
  1. Class III/IV heart failure
  2. MI or cardiac surgery in prior 3 months
  3. Severe renal/hepatic disease
  4. Active malignancy
  5. Current/recent (within 6 months) enrollment in weight loss program
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
AF CARE plus Usual CareAF CAREPatients will interface with the digital application.
AF CARE plus Usual CareUsual CarePatients will interface with the digital application.
Pilot TestingAF CAREPatients interface with the digital application, providing feedback on usability and satisfaction.
Usual Care then AF CareUsual CareAfter a 6 month period of usual care only, patients will interface with the digital application.
Primary Outcome Measures
NameTimeMethod
Percentage of Emails Opened and Clicked ThroughBaseline through month 6

Percentage of emails opened, and of those opened, the percentage of emails clicked through

Percentage of Text Messages That Were ReviewedBaseline through month 6
Cardiovascular Risk Factor ScoreBaseline, month 3, month 6, and month 12

The American Heart Association Life Simple 7 (LS7) is a calculated score using lab values, biometric measurements, and patient dietary responses. Score range: 0 to 10; 0 = most risk, 10 = least risk

Secondary Outcome Measures
NameTimeMethod
Change From Baseline in AF Symptom SeverityBaseline, month 3, month 6, and month 12

AF symptom severity assessed with the Atrial Fibrillation Symptoms Severity Scale (AFSS). The AFSS is a patient self-reported questionnaire that contains 21 questions, with 7 questions that provide calculated scores for AF symptom severity (0-35) with higher scores representing greater severity.

Change From Baseline in AF Symptom BurdenBaseline, month 3, month 6, and month 12

AF symptom burden assessed with the Atrial Fibrillation Symptom Severity Scale. The AFSS is a patient self-reported questionnaire that contains 21 questions that provides calculated scores for AF Burden, calculated in the following manner; AF Burden = AF frequency + AF duration + AF severity. Each of the 3 measures contribute equally to the AF burden score, and each measure ranges from 1-10 to yield Total AF Burden scores ranging from 3-30. Higher scores indicate greater AF burden.

Change From Baseline in Knowledge Related to Atrial FibrillationBaseline, month 3, month 6, and month 12

AF knowledge assessed with the Jessa AF Knowledge Score calculated from a 16 question self- reported questionnaire with a scoring range from 0-16, 16 indicating greater knowledge.

Change From Baseline in AF Quality of Life ScoreBaseline, month 3, month 6, and month 12

Quality of Life assessed using a patient completed questionnaire, Atrial Fibrillation Effect on Quality of Life Questionnaire (AFEQT). The AFEQT score is a combined score of 21 items; overall score range is 21 to 100, with a higher score representing greater QOL.

Trial Locations

Locations (1)

Stanford Health Care

🇺🇸

Stanford, California, United States

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