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Clinical Trials/NCT04050982
NCT04050982
Terminated
Not Applicable

Feasibility Study to Improve Atrial Fibrillation Outcomes Using a Digital Application for Cardiovascular Risk Reduction: Precursor to a Multicenter Randomized Trial

Stanford University1 site in 1 country11 target enrollmentOctober 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Atrial Fibrillation
Sponsor
Stanford University
Enrollment
11
Locations
1
Primary Endpoint
Percentage of Emails Opened and Clicked Through
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

The pilot portion of this study is to determine the feasibility of utilizing AF CARE to provide lifestyle modification support to patients with atrial fibrillation (AF).

The prospective, RCT portion of this study compare cardiovascular risk factors (CVRF), AF knowledge, AF Symptom Severity and Burden, and QOL between and within the wait list group and the AF CARE group at baseline, 3, 6, and 12 months.

Registry
clinicaltrials.gov
Start Date
October 1, 2019
End Date
January 26, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Paul Wang

Director, Stanford Electrophysiology and Arrhythmia Service

Stanford University

Eligibility Criteria

Inclusion Criteria

  • BMI \> 28 kg/m2 AND one additional CVRF using LS7
  • Access and willingness to engage in digital technology
  • Has a valid email address and a cell phone number
  • Able to ambulate
  • Able to speak/read English

Exclusion Criteria

  • Class III/IV heart failure
  • MI or cardiac surgery in prior 3 months
  • Severe renal/hepatic disease
  • Active malignancy
  • Current/recent (within 6 months) enrollment in weight loss program

Outcomes

Primary Outcomes

Percentage of Emails Opened and Clicked Through

Time Frame: Baseline through month 6

Percentage of emails opened, and of those opened, the percentage of emails clicked through

Percentage of Text Messages That Were Reviewed

Time Frame: Baseline through month 6

Cardiovascular Risk Factor Score

Time Frame: Baseline, month 3, month 6, and month 12

The American Heart Association Life Simple 7 (LS7) is a calculated score using lab values, biometric measurements, and patient dietary responses. Score range: 0 to 10; 0 = most risk, 10 = least risk

Secondary Outcomes

  • Change From Baseline in AF Symptom Severity(Baseline, month 3, month 6, and month 12)
  • Change From Baseline in AF Symptom Burden(Baseline, month 3, month 6, and month 12)
  • Change From Baseline in Knowledge Related to Atrial Fibrillation(Baseline, month 3, month 6, and month 12)
  • Change From Baseline in AF Quality of Life Score(Baseline, month 3, month 6, and month 12)

Study Sites (1)

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