跳至主要内容
临床试验/CTRI/2021/03/031950
CTRI/2021/03/031950尚未招募2/3 期

To Evaluate the efficacy of Vamana dhauti with and without Shivapalapindi in Amlapitta

Dr Chaudhari Krishnakumari B1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2021年3月15日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Reduce in the sign and symptoms of Amlapitta

研究概览

简要总结

Amlapittais a primary disorder of annavaha strotas, caused by vitiation oftridoshas which leads to mandagni causing vidagdhajirna whichin turns leads to vidahi condition. It is characterized by avipaka,klama, tikta-amlodgara, hrud kanta daha, gaurva, aruchi1.Theabove symptoms resemble gastric esophageal reflux diseases, which has signs andsymptoms of heart burn, regurgitation, nausea, indigestion2.

The prevalence of GERD in India islikely to be between 8 - 19% 3. Mostly it is seen in 2nd decade oflife. Several factors like change in lifestyle in terms of culture, smoking anduse of specific food types have contributed to the increased prevalence of GERDin this rapidly progressing society. Though antacids are the most recommendedtreatment in GERD, it is not permanent treatment to cope up with the currentsituation. The long term use of antacids can bring side effects includingdiarrhoea, constipation, changes in metabolism and build up of magnesium. So, there is need ofevolving more effective treatment which relives human sufferings.

Even though there are hundreds ofmedicinal combination are mentioned in the classics for amlapitta, veryfew of such medicinal measures are proved by clinical study, hence it is a needof hour to explore the efficacy of remaining ones.

Vamana dhauti is one among the shadkarma,which is practiced for the removal of kapha pitta dosha4.It acts over amasaya, which is the prime seat of amlapitta. It neutralizesthe acid balance in stomach and relives the symptoms.

Shivapalapindi contains dravyaslike Patha, Patola, Yava, Chandana, Dhanyaka,  Amalaki, Vasa, Lavanga, Tvak, Gaja pippli , Haritaki, Madhu, Sita and Ghrita5, which are kapha-pittaharain nature along with  dipana, pachana, anulomana, grahiproperties.

Hence in this study Vamanadhautiand Shivapalapindi are taken as interventions which may help in reducingthe signs & symptoms of amlapitta.

In this regard the study planned – “To Evaluatethe efficacy of Vamana dhautiwith and without Shivapalapindi in Amlapitta†is being undertaken.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
All

入选标准

  • Subjects between the age group of 18 to 40 yrs, irrespective of gender, religion, occupation & socio.
  • economic status.
  • Subjects having the Classical symptoms of amlapitta as described in Ayurvedic literature will be included.

排除标准

  • Subjects with any other systemic illness like Hypertension, Diabetes mellitus.
  • Previously diagnosed cases of ulceration of stomach, esophagus, and duodenum, CA of G.I tract and crohn’s disease.
  • Subjects who are not fit for Vaman dhauti will be excluded.
  • Pregnant lady & lactating women will be excluded.

结局指标

主要结局

Reduce in the sign and symptoms of Amlapitta

时间窗: 30 days

次要结局

  • other associated symptoms of amlapitta will reduce.(45 days)

研究者

发起方
Dr Chaudhari Krishnakumari B
申办方类型
Other [PG Scholar]

研究点 (1)

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