Vibration-induced Reflex Responses and Estimation of Tonic Vibration Latency
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Presynaptic inhibition level
研究概览
简要总结
The aim of this study is to estimate tonic vibration latency and whole body vibration reflex latency
详细描述
This study was included 17 patients with spastic spinal cord lesions and 23 healthy control.
Soleus T-reflex, soleus H-reflex, soleus tonic vibration reflex (TVR), and reflex muscle response induced by whole body vibration was evaluated this study. To obtain the H-reflex response, the tibial nerve in the popliteal region was stimulated by using a stimulator (FE155 Stimulator HC ADInstrument, Oxford UK) with 1 ms-pulse current. The records was taken with the Ag / AgCl electrodes (Kendall ®Coviden, self-adhesive electrodes) placed on skin according to the SENIAM protocol. To obtain T-reflex response, an electronic reflex hammer (Elcon 100-150 Germany) was used. After H-reflex and T reflex records at rest, to obtain Tonic vibration reflex, local vibration was applied to the Achilles tendon at 50, 85, 140, 185, 235 and 265 Hz. To obtain the reflex response induced by Whole body vibration, vibration was applied at 35, 37, 39, 41, 43 and 45 Hz. Tibial nerve stimulation was performed again to determine Hmax during whole body vibration and local vibration.H-reflex records was taken while the subject is sitting on a chair.
The data was recorded with the PowerLab data acquisition device (ADInstrument Oxford UK). For Whole-body vibration, PowerPlate Pro5 (London UK) was used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •spinal cord injury patients:
- •Spastic spinal cord lesion
- •Patients between the ages of 20 and 45
排除标准
- •for spinal cord injury patients
- •Accompanying trauma
- •Lower extremity fracture
- •Lower extremity peripheral nerve lesions
- •Head trauma
- •Autonomic dysreflexia
- •Heterotopic ossification
- •Lesions in calf skin
- •Excessive spasticity (Ashwort4) / Contracture (knee, hip, footbath)
- •Peripheral nerve-vascular diseases / muscle diseases
- •Pressure ulcer (> Grade 2)
- •Inclusion criteria for Control
- •Ages 20 and 45 old years
- •Healthy volunteers
- •Exclusion Criteria for Control
- •Pregnant women
研究组 & 干预措施
Vibrator
Local or Whole body vibration was applied at six different frequencies to Healthy control and spastic spinal cord injury. For local vibration, vibration frequencies were 50, 85, 140, 185, 235 and 265 Hz . For whole body vibration, vibration frequencies were 35, 37, 39, 41, 43 and 45 Hz
干预措施: vibrator (Device)
结局指标
主要结局
Presynaptic inhibition level
时间窗: 1 day
Change in Hmax amplitude during vibration
次要结局
未报告次要终点