Comparison of Neuromonitoring Devices in Predicting Raised ICP and Outcome in ALF Patients.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Comparison of Trans Cranial Doppler with Near Infrared Spectroscopy, BI-Spectral Index and Optic Nerve Sheath Diameter in predicting raised Intra Cranial Pressure related mortality in Acute Liver Failure patient.
研究概览
简要总结
Studies are scarce and limited data is available about the use of different noninvasive neuromonitoring devices in acute liver failure patients and their correlation in predicting the outcome.
All acute liver failure patients getting admitted in the ICU will be attached Near Infrared Spectroscopy and Bis electrodes and their charting will be done every hourly.
Optic nerve sheath diameter and Pulsatality index values will be noted at admission and every 6hourly till the final outcome of the patient.
These parameters will be observed in operation theatre if patient goes for Liver transplant.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Acute Liver Failure Patients.
排除标准
- •Acute on Chronic Liver Failure Patients.
- •Transcranial Doppler Window cannot be obtained.
结局指标
主要结局
Comparison of Trans Cranial Doppler with Near Infrared Spectroscopy, BI-Spectral Index and Optic Nerve Sheath Diameter in predicting raised Intra Cranial Pressure related mortality in Acute Liver Failure patient.
时间窗: Outcome will be assessed at baseline and every 6hourly
次要结局
- Optic Nerve Sheath Diameter & TransCranial Doppler values will be compared.(Degree of agreement between Optic Nerve Sheath diameter, PI values, BIS & NIRS)
研究者
Dr Aviral Srivastava
Institute Of Liver and Biliary Sciences