Changes in food preference and food cue responsivity after bariatric surgery

Recruiting

• Conditions: corpulence; morbide obesitas; morbid obesity; 10003018

• Registration Number: NL-OMON40362
• Lead Sponsor: Wageningen Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Scheduled for Roux-en-Y gastric bypass surgery
Age: 18-55 years
(for food cue response-part: normosmic)

Exclusion Criteria

Being a vegetarian
Allergic to food products used as stimuli in the study
(for food cue response-part: not being MRI compatible, i.e. having pieces of metal in the body)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Difference in food preferences before and after gastric bypass surgery.<br /><br>Difference in brain reward response to the smell and sight of food 2 weeks<br /><br>before and 8-10 weeks after gastric bypass surgery. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary objective is to assess fasting plasma levels of endocannabinoids<br /><br>(eCB), ghrelin, leptin, adiponectin, GLP1 and insulin.<br /><br>Differences in brain reward response (fMRI) after exposure to sight+smell and<br /><br>after exposure to smell alone.</p><br>