Role of preoperative nutrition in healing and recovery in children undergoing surgery

Completed

Brief Summary: Malnutrition among hospitalized children is known to negatively influence their response to therapy and to prolong their admission especially in a surgical setting. It also has short and long term consequences for growth development and well being. There is no study describing the prevalence of malnutrition among hospital children undergoing surgery in an Indian setting.

Problems exist in evaluating the effect of preoperative malnutrition on surgical outcomes due to a lack of unified definition of malnutrition assessment techniques and a paucity of randomized controlled trials correlating a statistically significant relationship between preoperative malnutrition and post operative outcomes.

Our study proposes to study the prevalence of malnutrition in a hospital setting assess each variable ie anthropometric values biochemical markers and subjective assessment in diagnosing malnutrition and predicting adverse events in such children. This will help us develop a low cost reliable diagnostic scoring system able to predict nutritional associated complications ie NAC. This would also guide us to intervene in such children before surgical procedure so as to improve outcomes. This scoring system would become part of preoperative evaluations in all children being planned for surgery in future.

Recruitment & Eligibility

Inclusion Criteria

All infants and children above the age of 3 months requiring major surgical procedures will be included into the study.

Exclusion Criteria

Children requiring emergency surgery Children below 3 months of age Children with documented nutritional deficiency Children undergoing minor surgery Children with confounding factors, where outcome is unlikely to be related to nutrition.
Children with severe malnutrition status as documented on anthropometry, SGNA (subjective global nutritional assessment) or standard biochemical analysis.

Primary Outcome Measures

Name	Time	Method
1 Estimate the prevalence of micronutrient deficiency in children undergoing major surgery.	The blood samples will be collected and stored as per lab requirements. they will be analysed for the values in batches of 50-100. This would approximately be once in 3 months based on our hospital statistics. final assessment will be at completion of study ( 300 now)
2 Outline the relationship between micro nutrient deficiency and clinical outcomes in children undergoing non-emergent surgery	The blood samples will be collected and stored as per lab requirements. they will be analysed for the values in batches of 50-100. This would approximately be once in 3 months based on our hospital statistics. final assessment will be at completion of study ( 300 now)

Secondary Outcome Measures

Name	Time	Method
1 To correlate micronutrient deficiency, anthropometry and conventional nutritional parameters to identify and define pre-surgical nutritional indicators predictive of nutrition related complications so as to aid in development of uniform screening tools that suits Indian population	2 Evidence-based analysis of the impact of micro nutrient deficiency on patient outcomes

Locations (2): Indira Gandh iInstitute of Child health
🇮🇳
Bangalore, KARNATAKA, India
Indira Gandhi Institute of Child Health
🇮🇳
Bangalore, KARNATAKA, India
Indira Gandh iInstitute of Child health
🇮🇳Bangalore, KARNATAKA, India
Dr Gowri Shankar
Principal investigator
9845804491
bcgshankar@gmail.com