A Prospective, Controlled Study of Rehabilitation of Anomia in Aphasia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 2
- 主要终点
- Spoken Word Production (Confrontation Naming)
研究概览
简要总结
This is a behavioral speech therapy trial for individuals who have suffered a stroke on the left side of the brain and have difficulty speaking. The name of this disorder is called "aphasia." Individuals in this study will receive one of two treatments. The first is a phonological (sound level) treatment and the second is a semantic (word level) treatment. Individuals in both groups will receive 60 hours of therapy for free (2 hours/day, 5 days/week, 6 weeks).
详细描述
Purpose: The ultimate goal of anomia treatment should be to achieve gains in exemplars trained in the therapy session as well as generalization to untrained exemplars and contexts. Phonomotor treatment (PMT) has shown such effects but has not yet been compared to a commonly used lexical/semantic based treatment (semantic feature analysis; SFA).
Methods: In a between group randomized controlled trial, 58 persons with aphasia characterized by anomia and phonological dysfunction were randomized to receive 56-60 hours of intensively delivered treatment over 6 weeks with testing pre-, post- and three-months post treatment termination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Single, left-hemisphere stroke
- •English as primary language prior to stroke
排除标准
- •Other neurological disorders
- •Untreated depression
研究组 & 干预措施
Phonomotor therapy
Experimental group
干预措施: Phonomotor Therapy (Behavioral)
Semantic Feature Analysis therapy
Current standard of care therapy
干预措施: Semantic Feature Analysis therapy (Behavioral)
结局指标
主要结局
Spoken Word Production (Confrontation Naming)
时间窗: Pretreatment to 3 months following treatment termination change
Reporting a change in percent correct scores pre-treatment versus 3-months post treatment. (0-100% scale)
次要结局
- Response Latency(Pretreatment to 3 months following treatment termination change)
- Verbs Correctly Named(Pretreatment to 3 months following treatment termination change)