跳至主要内容
临床试验/CTRI/2025/08/092141
CTRI/2025/08/092141尚未招募2/3 期

Evaluation of Pathadi Churna in management of Tundikeri in Children with special reference to Tonsillitis - A Randomised controlled clinical trial

KLE Ayurveda Hospital Belgavi1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年1月1日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
There might be significant effect of

研究概览

简要总结

Tonsillitis is an infection-related inflammation of the tonsils, frequently affecting school going children .The Incidence in school going children in India is 7% .About 7,455,494 cases of tonsillitis and 200,000 tonsillectomies are performed in India per year . Palatine tonsils represent the predominant immunocompetent tissue of upper respiratory tract. Its major function is as a first line of defence against viral, bacterial and food antigens that enter the upper aerodigestive system.

Another major function of the tonsils is to supply the local mucosal immune system of the upper respiratory tract with dimeric IgA-producing B cells. Secretory IgA has particular hydrophilic properties and is capable of preventing adsorption and penetration of bacteria and virus into upper respiratory tract mucosa .Tonsillitis of viral origin is usually treated with supportive care. Bacterial tonsillitis is most common caused by streptococcus pyogen .

Tonsillitis causes local immunological damages which lead to frequent development of the disease, hence affecting the child’s growth and development . The most widely used medication for tonsillitis are a group of antibiotics such as Penicillin, amoxicillin, erythromycin etc and surgery known as tonsillectomy, which are having adverse effect such as eruption of skin, nephrotoxicity, diarrhea, life threatening conditions like shock , post-operative bleeding, dehydration, uvular edema and damage or trauma to the adjacent anatomical tissue  . Hence there is a need for alternative treatment modality for the treatment of tonsillitis.

In Ayurveda Tonsillitis can be understood under the concept of tundikeri, which has various treatment modalities mentioned by Acharyas such as shaman aushadi, kavala , dhoompan, pratisarana, nasya etc. One of such shaman aushadhi mentoned by Acharya Charka is Pathadi churna, by virtue of its properties such as Galarogahara, vata pitta kaphahara doshaaghna, might be effecting in treating tundikeri (tonsillitis).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
6.00 Year(s) 至 16.00 Year(s)(—)
性别
All

入选标准

  • Patients of either sex in age group between 6years to 16years Patients fulfilling the diagnostic criteria will be included for the study Acute and Chronic Tonsillitis of Grade 1 and Grade 2.

排除标准

  • Children with fever more than 100 degree Farhenite Children with tonsillitis of grade 3 and 4 Subjects with complication of tonsillitis such as pre diagnosed Rheumatic Heart Disease Rheumatic fever Known cases of peritonsillar abscess tonsillar cyst and tonsilolith Known cases of Covid 19 and Acute and Chronic lower respiratory tract infection Children needing any form of acute management Children on any medication that may interfere with the outcome of trial drug example steroid antibiotics.

结局指标

主要结局

There might be significant effect of

时间窗: 0 day | 3 days | 7 days

Pathadi churna in the management of tundikeri with special reference to tonsillitis in children assessed through Tundikeri scoring scale McIssac score and Modified VAS scale

时间窗: 0 day | 3 days | 7 days

次要结局

  • Measured by changes in tonsillitis through Ayurveda scoring scale(0 day)

研究者

发起方
KLE Ayurveda Hospital Belgavi
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Jain Aditi Ajay

KLE Shri B M Kankanawadi Ayurveda Mahavidyalaya Belagavi

研究点 (1)

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