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A pilot study, The efficacy of topical 0.025% capsaicin gel in the treatment of lichen amyloidosis at Institute of dermatology, Thailand

Phase 2
Conditions
1. The patient was diagnosed lichen amyloidosis on both lower legs2. No Underlying disease more than Chronic kidney disease stage 4
lichen amyloidosis&#44
capsaicin
Registration Number
TCTR20191213001
Lead Sponsor
Institute of Dermatology, Bangkok, Thailand
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Enrolling by invitation
Sex
All
Target Recruitment
30
Inclusion Criteria

1. The patient was diagnosed lichen amyloidosis with bilateral smymmetrical lesions on both lower legs
2. All sex groups, 18-75 years old
3. Off previous medication including NSAIDs, steroid and antihistamine at least 4 weeks

Exclusion Criteria

1. History of anesthetic drugs allergy
2. Underlying disease; Asthma, Coronary artery disease, more than CKD stage 4
3. Chronic ulceration on lesion
4. Non-communication patient

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The Efficacy (convex and thickness) of skin lesion after topical 0.025% capsaicin gel at 0,4,8,12 wks Assess from picture by 3 board certified dermatologist
Secondary Outcome Measures
NameTimeMethod
The Efficacy (colors) of skin lesion after topical 0.025% capsaicin gel at 0,4,8,12 wks Assess from picture by 3 board certified dermatologist,The satisfy and pruritus symptoms after topical 0.025% capsaicin gel at 0,4,8,12 wks Self-assessment by the patient
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