NCT05952050
Recruiting
Not Applicable
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing General Anesthesia
Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.1 site in 1 country120 target enrollmentAugust 1, 2023
InterventionsDexmedetomidine
DrugsDexmedetomidine
Overview
- Phase
- Not Applicable
- Intervention
- Dexmedetomidine
- Conditions
- Dexmedetomidine
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- The frequency of delirium during the first 3 postoperative days
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient. The current study aimed to compare the effect of different administration routes of dexmedetomidine on POD in elderly patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Older than 65 years; General anesthesia for more than two hours;
Exclusion Criteria
- Not provided
Arms & Interventions
Intranasal dexmedetomidine
Intervention: Dexmedetomidine
Intravenous dexmedetomidine
Intervention: Dexmedetomidine
Outcomes
Primary Outcomes
The frequency of delirium during the first 3 postoperative days
Time Frame: 3 days
Secondary Outcomes
- The incidence of sleep quality(3 days)
- The incidence of postoperative sore throat(3 days)
Study Sites (1)
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