Different Administration Routes of Dexmedetomidine on Postoperative Delirium

Not Applicable

Recruiting

• Conditions: Dexmedetomidine; General Anesthesia; Postoperative Delirium
• Interventions: Drug: Dexmedetomidine

• Registration Number: NCT05952050
• Lead Sponsor: Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.

Brief Summary

Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient. The current study aimed to compare the effect of different administration routes of dexmedetomidine on POD in elderly patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-07
• Study First Submitted: 2023-07-11
• Study First Submitted QC: 2023-07-11
• Last Update Submitted: 2023-07-11
• Study First Posted: 2023-07-19
• Last Update Posted: 2023-07-19
• Study Start: 2023-08-01
• Primary Completion: 2023-08-01
• Study Completion: 2023-09-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Older than 65 years; General anesthesia for more than two hours;

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intravenous dexmedetomidine	Dexmedetomidine	-
Intranasal dexmedetomidine	Dexmedetomidine	-

Primary Outcome Measures

Name	Time	Method
The frequency of delirium during the first 3 postoperative days	3 days

Secondary Outcome Measures

Name	Time	Method
The incidence of postoperative sore throat	3 days
The incidence of sleep quality	3 days

Trial Locations

Locations (1)

Weitao Chen; 🇨🇳 Zhongshan, Guangdong, China