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Clinical Trials/NCT06523712
NCT06523712
Completed
Not Applicable

A Scalable, Equity-focused, Teacher-delivered, School-based Oral Health Intervention for Pakistani Lower Secondary Schoolchildren: a Pragmatic Cluster-randomized Effectiveness-implementation Trial (Smile Smarts-PK)

Universiti Putra Malaysia1 site in 1 country4,055 target enrollmentJuly 25, 2024

Overview

Phase
Not Applicable
Intervention
Smile Smarts
Conditions
Dental Plaque
Sponsor
Universiti Putra Malaysia
Enrollment
4055
Locations
1
Primary Endpoint
DENTAL HEALTH PRACTICES AND BEHAVIOUR
Status
Completed
Last Updated
16 days ago

Overview

Brief Summary

This was a pragmatic, two-arm, and parallel-group, superiority cluster-randomized controlled trial with 1:1 allocation of clusters (schools) to either the Smile Smarts-PK intervention arm or the control arm. The trial settings were lower secondary schools (classes 5-8) in the Punjab, Pakistan. Punjab is the most populous province of Pakistan; it has many public and low-cost private schools that serve lower- and middle-income communities.

Detailed Description

Oral diseases are among the most common non-communicable conditions affecting children worldwide and disproportionately burden those in low- and middle-income countries. Robust evidence from pragmatic, theory-informed, school-based cluster-randomized trials in South Asia remains scarce. We evaluated the effectiveness of Smile Smarts-PK, a scalable teacher-delivered oral health intervention embedded within routine lower secondary school systems in Pakistan. Methods It is a parallel, pragmatic, school-level cluster-randomized controlled trial in 50 lower secondary schools in Pakistan. Schools were randomly assigned (1:1) to either the Smile Smarts-PK intervention or usual school practice. The intervention was teacher-delivered, integrated into routine academic schedules, and informed by the Health Belief Model. Primary outcomes at 12 months were clinical oral health indices: Debris Index-Simplified (DI-S), Calculus Index-Simplified (CI-S), Oral Hygiene Index-Simplified (OHI-S). Secondary outcomes included plaque index, children's oral health knowledge, observed and self-reported oral health behaviours, and maternal knowledge, attitudes, and practices. Analyses were by intention to treat using linear mixed-effects models accounting for clustering at the school level.

Registry
clinicaltrials.gov
Start Date
July 25, 2024
End Date
July 15, 2025
Last Updated
16 days ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Arshed Muhammad

PhD studentship

Universiti Putra Malaysia

Eligibility Criteria

Inclusion Criteria

  • Age between 10 to 15 years. Enrollment at one of the selected schools.
  • Consent obtained from parents or legal guardians for participation in the study.

Exclusion Criteria

  • Children and their parents who did not give assent and consent to participate in the study.
  • Children with severe oral health issues require immediate medical attention.
  • Children with special needs affecting their ability to participate in the oral health education interventions.

Arms & Interventions

Smile Smarts-PK

The intervention group is given the Smile Smarts-PK intervention. It is s a multi-theory, multicomponent oral health promotion intervention grounded in a multi-level theoretical framework integrating the Health Belief Model (HBM) and Social Cognitive Theory (SCT). In addition, the delivery strategy is viewed through an implementation science lens, implementation theory, to strengthen understanding not only of effectiveness but also of reach, adoption, fidelity, and future maintenance.

Intervention: Smile Smarts

Control group

Participants assigned to Arm 2 serve as the control group and do not receive any intervention during the study except for routine school activities

Outcomes

Primary Outcomes

DENTAL HEALTH PRACTICES AND BEHAVIOUR

Time Frame: 6 MONTHS

The primary outcome is dental health practices and behaviour will be assessed using a pre-validated questionnaire derived from a reference study with a reliability score of 0.719. The questionnaire comprises 12 questions, where questions 1-6 pertain to awareness and questions 7-12 assess practices. The scoring range is from 0 to 12, with higher scores indicating better dental health practices and behavior.

Oral Hygiene Status

Time Frame: 12 month

The change in the Simplified Oral Hygiene Index (OHI-S) from baseline to 12 months served as the primary endpoint. The OHI-S scores debris and calculus on six index surfaces (scores 0-3 each), with the summed component means creating an overall score ranging from 0 (good hygiene) to 6 (poor hygiene). Scores were categorized as good (0.0-1.2), fair (1.3-3.0), or poor (3.1-6.0). The primary analysis focused on the change in mean OHI-S score at both the individual and cluster levels

Secondary Outcomes

  • ORAL HEALTH RELATED QUALITY OF LIFE(6 months)
  • GINGIVAL SCORE(6 MONTHS)
  • PLAQUE SCORE(6 MONTHS)
  • PLAQUE SCORE(12 months)
  • Observed toothbrushing performance(12 months)
  • Self-Reported Oral Hygiene Behaviors(12 months)
  • Mothers' Knowledge, Attitudes, and Practices (KAP)(12 months)

Study Sites (1)

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