Prospective Multicenter Cohort Study Evaluating the Incidence and Risk Factors for Problem Gambling Among Young Adults With First-episode Psychosis

Recruiting

• Conditions: Gambling Disorder; Psychotic Disorders
• Interventions: Drug: Dopamine partial agonists; Other: Psychiatric comorbidities; Other: Sex; Other: Gender; Other: Socioeconomic status; Other: Gambling history

• Registration Number: NCT05686772
• Lead Sponsor: Laval University

Brief Summary

The aim of this observational study is to get a better understanding of the association between problem gambling psychotic disorders among young adults with firs-episode psychosis. The main questions to be answered are:

1. What are the incidence and risk factors for problem gambling in this population?

2. How effective are the current treatments for problem gambling in adults with first-episode psychosis?

To do so, comparisons will be made among the study cohort for various factors:

* Use of dopamine partial agonists;

* Psychiatric comorbidities;

* Socioeconomic status;

* Sex;

* Gender;

* Gambling history.

The nature of the treatments for problem gambling offered and received by the subjects, as well as their effectiveness, will also be documented.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-01
• Study First Submitted: 2022-12-29
• Status Verified: 2023-01
• Study First Submitted QC: 2023-01-09
• Last Update Submitted: 2023-01-16
• Study First Posted: 2023-01-17
• Last Update Posted: 2023-01-18
• Primary Completion: 2024-05-01
• Study Completion: 2024-05-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• 18 to 35 years old;
• Diagnosis of first-episode psychosis (i.e., DSM-5 diagnosis of schizophrenia spectrum and other psychotic disorders, as well as DSM-5 bipolar disorder with psychotic features).

Exclusion Criteria

• DSM-5 diagnosis of psychotic disorder due to a medical condition;
• Severe intellectual disability.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
First-episode psychosis patients	Gender	-
First-episode psychosis patients	Psychiatric comorbidities	-
First-episode psychosis patients	Dopamine partial agonists	-
First-episode psychosis patients	Gambling history	-
First-episode psychosis patients	Sex	-
First-episode psychosis patients	Socioeconomic status	-

Primary Outcome Measures

Name	Time	Method
Gambling disorder	At 36 months	Diagnosis of gambling disorder according to DSM-5 criteria, established by the treating psychiatrist

Secondary Outcome Measures

Name	Time	Method
Problem gambling	At 36 months	Problem gambing according to a score of 8 and more on the Problem Gambling Severity Index, as questioned by the clinical case manager

Trial Locations

Locations (2)

Montreal University Hospital Center; 🇨🇦 Montreal, Quebec, Canada

Quebec Mental Health University Institute; 🇨🇦 Quebec, Canada