A comparative study examining the in vitro fermentation by ileal microbiota obtained from human ileostomy subjects and an animal model

Not Applicable

Completed

• Conditions: Human ileostomy subjects; Diet and Nutrition - Other diet and nutrition disorders; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12622000813785
• Lead Sponsor: Riddet Institute, Massey University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-12-03
• Study Start: 2022-06-09
• Last Update Posted: 13 June 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

They must have a well-established and normally functioning ileostomy following a total colectomy for ulcerative colitis with <10 cm of the terminal ileum removed.
BMI between 18 and 27 kg/m2.

Exclusion Criteria

They will not:
•Smoke cigarettes or take recreational drugs
•Have kidney failure or diabetes
•Have taken antibiotics or other medication that might affect the small intestinal microbial population within the three months before participating in the study
•Have an alcohol intake >2 standard drinks per day
•Be pregnant or breastfeeding
•Be intolerant or allergic to dairy products, wheat (including gluten) or apple.
•Be on a controlled diet or dietary weight loss regime for three months before participating in the study or during the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified