The effect of botulinum toxin type A on reducing salivation and quality of life in patients with cerebral palsy
Phase 1
- Conditions
- Cerebral palsy.Cerebral palsy
- Registration Number
- IRCT20220516054868N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Affliction cerebral palsy
Drooling score more than 4
Exclusion Criteria
Contraindications for injection of Botulinum toxin A
Botulinum toxin type A injection in three month ago
Perform recent maxillofacial surgery that may interfere with saliva production and flow
Receive systemic medication to treat sialorrhea in the last three months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount and intensity of saliva secretion based on drooling frequency and severity score. Timepoint: drooling frequency and severity Score before injection, 2 weeks after injection, one month, 2 months, 4 months and 6 months after injection. Method of measurement: drooling frequency and severity Score.
- Secondary Outcome Measures
Name Time Method Quality of life score related to salivation based on a questionnaire. Timepoint: Before injection, 2 weeks after injection, one month, 2 months, 4 months and 6 months after injection. Method of measurement: Teacher drooling scale.