Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor Hypomineralization

Not Applicable

Not yet recruiting

• Conditions: Dentine Hypersensitivity
• Interventions: Drug: nano hydroxy apatite varnish Intervention (1); Drug: Potassium Nitrate Gel; Drug: Varnishes, Fluorid

• Registration Number: NCT07056855
• Lead Sponsor: Cairo University

Brief Summary

This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing Dentin Hypersensitivity in MIH-affected teeth.

Detailed Description

This randomized clinical trial study aims to investigate the effectiveness of nano-hydroxy apatite crystal varnish, and potassium nitrate gel compared to fluoride varnish, in reducing dentin hypersensitivity, improving a child's oral hygiene.

Study Timeline

• Status Verified: 2025-03
• Study First Submitted: 2025-06-29
• Study First Submitted QC: 2025-06-29
• Last Update Submitted: 2025-06-29
• Study First Posted: 2025-07-09
• Last Update Posted: 2025-07-09
• Study Start: 2025-07-10
• Primary Completion: 2025-07-20
• Study Completion: 2025-07-20

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
8.6% nano-hydroxy apatite crystals varnish (Fygg's professional strength, Fygg, USA).	nano hydroxy apatite varnish Intervention (1)	Intervention group (1)
Potassium Nitrate (Ultradent UltraEZ Desensitizing Gel, Ultradent Inc., USA).	Potassium Nitrate Gel	Intervention group (2)
5% fluoride varnish Control group	Varnishes, Fluorid	-

Primary Outcome Measures

Name	Time	Method
Dentin Hypersensitivity	Baseline, 15 miutes pot-op, 2 weeks post-op, and 4 weeks post op	chiff Cold Air Blasting Sensitivity Scale: scores from 0-3. The higher the score the worse the sensitivity.

Secondary Outcome Measures

Name	Time	Method
Oral hygiene	baseline, 2-, and 4- week post-op	Measured by Plaque Control Record: Percentage.