Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Change in Cognitive function (MoCA)
研究概览
简要总结
This study investigates the neural mechanisms of cognitive function decline, cognitive assessment methods for subjects with mild cognitive dysfunction (Mild cognitive impairment, MCI, or cognitive decline milder than MCI), and the approaches used to improve and restore cognitive function.
详细描述
Cognitive assessment tools are used to assess cognitive function of subjects in different cities. Functional and structural MRI and EEG are applied to investigate the neural mechanisms of cognitive function decline and effects of methods to improve and restore cognitive function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults being able to walk at least a block, and
- •Adults with subjective cognitive decline (SCD), or
- •Adults with mild cognitive impairment (MCI), or
- •Adults with normal cognitive function
排除标准
- •Clinical diagnosis of dementia
- •Adults who cannot follow the protocal
结局指标
主要结局
Change in Cognitive function (MoCA)
时间窗: Change from Baseline Cognitive test results at 3 months.
The Montreal Cognitive Assessment test is used to assess cognitive function of participants.
Change in Cognitive function (AD8)
时间窗: Change from Baseline Cognitive test results at 3 months.
The AD8 test is used to assess cognitive function of participants.
Change in Cognitive function (CDR)
时间窗: Change from Baseline Cognitive test results at 3 months.
The Clinical Dementia Rating (CDR) test is used to assess cognitive function of participants.
Change in Cognitive function (SCD-9)
时间窗: Change from Baseline Cognitive test results at 3 months.
The SCD-9 questionnaire is used to assess cognitive function of participants.
次要结局
- Change in Physical capacity (TUG)(Change from Baseline physical capacity test results at 3 months.)
- Change in Physical capacity (chair standing)(Change from Baseline physical capacity test results at 3 months.)
研究者
Pengxu Wei
Director
National Research Center for Rehabilitation Technical Aids