ACTRN12612001239853
Recruiting
Phase 1
A placebo controlled clinical trial on the efficacy of inhaled verapamil 10 mg stat administration in patients with chronic obstructive pulmonary disease (COPD) and pulmonary arterial pressure(PAP)>45 mmHg.
Shahid Beheshti University, M.C.0 sites30 target enrollmentNovember 23, 2012
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Pulmonary hypertension secondary to chronic obstructive pulmonary disease (COPD)
- Sponsor
- Shahid Beheshti University, M.C.
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with pulmonary arterial pressure (PAP)\>45mmHg secondary to chronic obstructive pulmonary disease (COPD) and normal ejection fraction (EF) (\> 40%).
Exclusion Criteria
- •1\.Pregnancy 2\.Patients with previous known hypersensitivity to verapamil (any formulation or route of administration) 3\. Patients with sepsis 4\. Patients with dysrythmia or heart block (second degree and third degree). 5\.Patients with COPD exacerbation 6\.Any contraindication for verapamil 7\.Presence of an end stage disease (cardiac, renal and hepatic) 8\.Patients receiving another calcium channel blocker (CCB), sildenafil and bosentan .
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Phase 1
A placebo controlled clinical trial on the efficacy of atorvastatin 20 mg daily in patients with bronchial hyper-responsiveness.bronchial hyper-responsivenessRespiratory - AsthmaACTRN12609000704291Shahid Beheshti University, M.C.40
Active, not recruiting
Phase 1
Efficacy and tolerability study of pregabalin in carcer induced bone pain.Treatment of moderate to severe chronic bone pain related to metastatic cancer.MedDRA version: 14.1Level: LLTClassification code 10049038Term: Metastatic bone painSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)Therapeutic area: Diseases [C] - Cancer [C04]EUCTR2006-002486-39-ESPFIZER S310
Completed
Phase 3
A randomised controlled trial of the efficacy of a carrageenan nasal spray when taken during a cold in reducing asthma exacerbations as measured by the asthma control questionnaire.Asthma exacerbation during a coldColdsRespiratory - AsthmaInfection - Studies of infection and infectious agentsACTRN12615001166561Julian Crane361
Active, not recruiting
Not Applicable
A randomized placebo-controlled clinical trial of topical photodynamic therapy with a nanoemulsion formulation of 5-aminolevulinic acid for the treatment of actinic keratosisEUCTR2006-000314-20-DEBiofrontera Bioscience GmbH260
Completed
Not Applicable
A randomized placebo controlled clinical trial of a rehabilitation programme for patients with a diagnosis of massive, irreparable rotator cuff tears of the shoulderISRCTN64734872Record Provided by the NHSTCT Register - 2006 Update - Department of Health60