Internet-delivered Attention Training for Obsessive-Compulsive Disorder

Not Applicable

Completed

• Conditions: Obsessive-Compulsive Disorder
• Interventions: Behavioral: Attention Training Program

• Registration Number: NCT02018848
• Lead Sponsor: Humboldt-Universität zu Berlin

Brief Summary

The goal of this study is to investigate an attention training program for participants with Obsessive-Compulsive Disorder. The attention training consists of a modified dot probe task with picture stimuli related to washing and checking paired with neutral pictures.

Participants are randomly assigned to an experimental and a placebo-control group. After a minimum of 4 weeks of attention training we expect to find differences between participants of the experimental and the control group in terms of attention bias, OCD symptoms, anxiety and depression.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-10
• Study First Submitted: 2013-11-28
• Study First Submitted QC: 2013-12-17
• Study First Posted: 2013-12-23
• Primary Completion: 2014-07
• Study Completion: 2014-07
• Status Verified: 2014-11
• Last Update Submitted: 2014-11-11
• Last Update Posted: 2014-11-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

• diagnosis of primary OCD according to OCI-R self report (cut-off >=18)

Exclusion Criteria

• suicidal
• substance abuse or addiction
• psychotic symptoms
• visual impairment if not compensated with optical aid

Current treatment is not an exclusion criterion, but data on treatment status (current psycho- or pharmacotherapy for OCD) will enter our statistical analyses.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Attention Training Program	Attention Training Program	The Attention Training consists of a modified dot-probe task. In this task pairs of pictures (OCD-relevant/neutral) are presented for 500 ms on a computer screen. Next, a probe appears on one of the two former picture locations. Participants have to react to that probe by pressing the corresponding button on the keyboard. One training session takes approximately 10 minutes in which 160 stimulus pairs are shown. In the experimental group the probe always appears at the location of the neutral picture so as to train attention away from OCD-relevant stimuli. Participants are asked to complete at least 2 training sessions per week over a period of 5 weeks. The first and last session are bias assessment sessions (see outcome measures), but participants stay blind to this.

Primary Outcome Measures

Name	Time	Method
Yale-Brown Obsessive-Compulsive Scale Self-Report Scale (Y-BOCS-SRS) T1	pre-treatment, estimated: between day 1 and day 7 after enrolment (no time limit set)	The Y-BOCS-SRS measures severity of OCD symptoms.
Yale-Brown Obsessive-Compulsive Scale Self-Report Scale (Y-BOCS-SRS) T2	post-treatment, between day 1 and 6 after T2 Bias Assessment (time limit set)	The Y-BOCS-SRS measures severity of OCD symptoms.
Yale-Brown Obsessive-Compulsive Scale Self-Report Scale (Y-BOCS-SRS) T3	follow-up, between day 27 and 50 after T2 questionnaires (time limit set)	The Y-BOCS-SRS measures severity of OCD symptoms.

Secondary Outcome Measures

Name	Time	Method
Obsessive-Compulsive Inventory-Revised (OCI-R) T1	pre-treatment, estimated: between day 1 and day 7 after enrolment (no time limit set)	The OCI-R measures severity of OCD symptoms.
Obsessive-Compulsive Inventory-Revised (OCI-R) T2	post-treatment, between day 1 and 6 after T2 Bias Assessment (time limit set)	The OCI-R measures severity of OCD symptoms.
Obsessive-Compulsive Inventory-Revised (OCI-R) T3	follow-up, between day 27 and 50 after T2 questionnaires (time limit set)	The OCI-R measures severity of OCD symptoms.

Trial Locations

Locations (1)

Humboldt-Universität zu Berlin; 🇩🇪 Berlin, Germany