Coagulation Parameters During Pregnancy in Amniotic Fluid
- Conditions
- Pregnancy
- Registration Number
- NCT00458666
- Lead Sponsor
- Rambam Health Care Campus
- Brief Summary
Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.
- Detailed Description
Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 170
- Women undergoing amniocentesis during 15-35 weeks of gestation.
- A history of venous thromboembolism
- Systemic disease i.e.; diabetes, hypertension, hypo or hyper-thyroidism,
- Anticoagulant treatment
- Abnormal embryo
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Dept of Obstetrics and Gynecology, Rambam-Health Care Campus
🇮🇱Haifa, Israel